Results 1 to 10 of about 2,242,374 (316)

Benefit of prompt initiation of single-inhaler fluticasone furoate, umeclidinium, and vilanterol (FF/UMEC/VI) in patients with COPD in England following an exacerbation: a retrospective cohort study

Respiratory Research, 2023
Background Triple therapy is recommended for patients with chronic obstructive pulmonary disease (COPD) who remain symptomatic despite dual therapy. The optimal timing of triple therapy following an exacerbation of COPD is unknown. The outcomes of prompt
Afisi S. Ismaila, Kieran J. Rothnie, Robert P. Wood, Victoria L. Banks, Lucinda J. Camidge, Alexandrosz Czira, Chris Compton, Raj Sharma, Shannon N. Millard, Olivia Massey, David M. G. Halpin   +10 more
doaj   +1 more source

Characterisation of patients with chronic obstructive pulmonary disease initiating single-device inhaled corticosteroids/long-acting β2-agonist dual therapy in a primary care setting in England

BMJ Open Respiratory Research, 2022
Introduction Treatment pathways of patients with chronic obstructive pulmonary disease (COPD) receiving single-device dual therapies in England remain unclear.
Victoria Banks, Robert Wood, Gema Requena, Alexandrosz Czira, Theo Tritton, Rosie Wild, Chris Compton, Maria Duarte, Afisi S Ismaila   +8 more
doaj   +1 more source

Real-World Evidence: A Primer

Journal of Orthopaedic Trauma, 2021
Summary: The insights that real-world data (RWD) can provide, beyond what can be learned within the traditional clinical trial setting, have gained enormous traction in recent years. RWD, which are increasingly available and accessible, can further our understanding of disease, disease progression, and safety and effectiveness of treatments ...
Robert, Zura, Debra E, Irwin, Christina D, Mack, Molly L, Aldridge, John I, Mackowiak   +4 more
openaire   +3 more sources

Public health impact and cost-effectiveness of catch-up 9-valent HPV vaccination of individuals through age 45 years in the United States

Human Vaccines & Immunotherapeutics, 2021
The Advisory Committee on Immunization Practices (ACIP) recommended catch-up 9-valent Human Papillomavirus (HPV) vaccination through age 26 years, and shared clinical decision-making for adults aged 27–45 years, compared with catch-up through age 26 ...
Vincent Daniels, Vimalanand S. Prabhu, Cody Palmer, Salome Samant, Smita Kothari, Craig Roberts, Elamin Elbasha   +6 more
doaj   +1 more source

Assessing the use of antibiotics and the burden of varicella in Belgium using a retrospective GP database analysis

BMC Infectious Diseases, 2021
Background Varicella is a highly contagious infection that typically occurs in childhood. While most cases have a generally benign outcome, infection results in a considerable healthcare burden and serious complications may occur.
Jessica Vandenhaute, Elyonore Tsakeu, Pierre Chevalier, Manjiri Pawaskar, Goran Benčina, Jan Vertriest   +5 more
doaj   +1 more source

Real-World Evidence for Equality

Health Equity, 2021
As stakeholders in the transformative medical research ecosystem, real-world evidence researchers must conduct observational research with an awareness of racism. Advancements in understanding of the impact of racism on health outcomes, the abundance of health care data, and innovations in health information technology provide tools that create ...
C. Erwin Johnson, Yohance Omar Whiteside
openaire   +3 more sources

Clinical, economic, and humanistic burden of community acquired pneumonia in Europe: a systematic literature review

Expert Review of Vaccines, 2023
Background Community-acquired pneumonia (CAP) is an infectious lung inflammation contracted outside the hospital. CAP is a leading cause of death among young children, elderly, and immunocompromised persons. Incidence can reach 14 cases/1,000 adults.
Eleana Tsoumani, John A Carter, Stina Salomonsson, Jennifer M Stephens, Goran Bencina   +4 more
doaj   +1 more source

Recommendations and Health Technology Assessment (HTA) landscape evaluation for pediatric pneumococcal conjugate vaccines (PCV) in Europe: A systematic literature review

Human Vaccines & Immunotherapeutics, 2022
National Immunization Technical Advisory Groups (NITAGs) and Health Technology Assessment (HTA) agencies evaluate the value of vaccines and provide decision-making authorities with recommendations.
Goran Bencina, Hanna Fues Wahl, Eleana Tsoumani, Stina Salomonsson   +3 more
doaj   +1 more source

Asthma control among treated US asthma patients in Practice Fusion’s electronic medical record research database

npj Primary Care Respiratory Medicine, 2023
This study investigated burden of ‘not well-controlled’ asthma, overall and by Global Initiative for Asthma (GINA) Step, among treated asthma patients in Practice Fusion’s research database.
Jonathan Davitte, Bailey DeBarmore, David Hinds, Shiyuan Zhang, Jessica Chao, Leah Sansbury   +5 more
doaj   +1 more source

Short and long-term costs among women experiencing preterm labour or preterm birth: the German experience

BMC Pregnancy and Childbirth, 2018
Background Preterm labour and birth (PTL/PTB) is characterised by major health and developmental risks for children, life–changing consequences for their families, and substantial healthcare and economic challenges for wider society.
Shibani Pokras, Jeanne Pimenta, Evie Merinopoulou, Dimitra Lambrelli   +3 more
doaj   +1 more source