Results 31 to 40 of about 16,717,089 (314)

Treatment pathways, economic burden and clinical outcomes in new users of inhaled corticosteroid/long-acting B2-agonist dual therapy with chronic obstructive pulmonary disease in a primary care setting in England: a retrospective cohort study

BMJ Open
Objective Management of chronic obstructive pulmonary disease (COPD) with inhaled corticosteroid/long-acting β2-agonist (ICS/LABA) improves lung function and health status and reduces COPD exacerbation risk versus monotherapy.
Victoria Banks, Robert Wood, Gema Requena, Alexandrosz Czira, Theo Tritton, Rosie Wild, Chris Compton, Afisi Ismaila   +7 more
doaj   +1 more source

Impact of "time zero" of Follow-Up Settings in a Comparative Effectiveness Study Using Real-World Data with a Non-user Comparator: Comparison of Six Different Settings

Drugs - Real World Outcomes, 2022
Background Time-related bias can lead to misleading conclusions. Properly setting the "time zero" of follow-up is crucial for avoiding these biases. However, the time-zero setting is challenging when comparing users and non-users of a study drug because ...
Ryozo Wakabayashi, Takahiro Hirano, Thomas Laurent, Yoshiki Kuwatsuru, Ryohei Kuwatsuru   +4 more
doaj   +1 more source

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

World Bank Group Evaluation Principles [PDF]

, 2019
The World Bank Group is committed to its twin goals: to eradicate extreme poverty and boost shared prosperity in a sustainable manner. The World Bank Group’s Forward Look – A Vision for the World Bank Group in
World Bank
core   +1 more source

Correlation between pathological complete response and prognosis in patients with breast cancer: real world data from the Brazilian Public Health System.

, 2023
Retrospective cohort study with female patients over 18 years of age, with non-metastatic CM diagnosis, undergoing NAC. pCR was considered as the absence of invasive or in situ residual tumor in the breast and axilla.
MARCELO ANTONINI
core   +1 more source

Evaluating the Performance of High-Dimensional Propensity Scores Compared with Standard Propensity Scores for Comparing Antihypertensive Therapies in the CPRD GOLD Database

Cardiology and Therapy, 2023
Introduction Propensity score (PS) matching is widely used in medical record studies to create balanced treatment groups, but relies on prior knowledge of confounding factors.
Virginie Simon, Jade Vadel
doaj   +1 more source

Real-world treatment patterns and outcomes among individuals receiving first-line pembrolizumab therapy for recurrent/metastatic head and neck squamous cell carcinoma

Frontiers in Oncology, 2023
BackgroundPembrolizumab, a PD-1 immune checkpoint inhibitor, is approved as first-line (1L) treatment for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) as monotherapy or in combination with platinum and 5-fluorouracil ...
Christopher M. Black, Glenn J. Hanna, Liya Wang, Karthik Ramakrishnan, Daisuke Goto, Vladimir Turzhitsky, Gleicy M. Hair   +6 more
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Real-World Evidence Analysis of a Hybrid Closed-Loop System. [PDF]

BACKGROUND We analyzed real-world evidence to assess the performance of the mylife CamAPS FX hybrid closed-loop system. METHODS Users from 15 countries across different age groups who used the system between May 9, 2022, and December 3, 2022 ...
Hovorka, Roman, Ruan, Yue, Wilinska, Malgorzata E, Alwan, Heba, Da Silva, Julien   +4 more
core   +2 more sources

Interim Effectiveness of 2025–2026 mRNA-1283 and BNT162b2 COVID-19 Vaccines Against COVID-19-Related Outcomes Among Adults Aged ≥ 65 Years in the United States

Infectious Diseases and Therapy
Introduction The 2025–2026 COVID-19 vaccine season introduced updated formulations targeting the LP.8.1 lineage. This interim analysis assessed absolute vaccine effectiveness (aVE) of mRNA-1283 and BNT162b2 on COVID-19 outcomes in adults aged ≥ 65 years.
Nevena Vicic, Alina Bogdanov, Heather Hensler, Taylor Ryan, Ni Zeng, Ekkehard Beck, Emily Patry, Machaon Bonafede, Andre B. Araujo, Amanda Wilson   +9 more
doaj   +1 more source