Results 11 to 20 of about 16,717,089 (314)

Creating and using real-world evidence to answer questions about clinical effectiveness [PDF]

, 2015
New forms of evidence are needed to complement evidence generated from randomised controlled trials (RCTs). Real-World Evidence (RWE) is a potential new form of evidence, but remains undefined.This paper sets to fill that gap by defining RWE as the ...
Crawford, Laura, Neil Munro, de Lusignan, Simon, Munro, Neil, Simon de Lusignan, Laura Crawford   +5 more
core   +1 more source

Real-World Evidence: A Primer

Pharmaceutical Medicine, 2023
Real-world evidence (RWE) is clinical evidence on a medical product's safety and efficacy that is generated using real-world data (RWD) resulting from routine healthcare delivery. There are several sources of RWD, including electronic health records (EHRs), registries, claims/billing data, and patient-generated data, as well as those from mobile health
openaire   +2 more sources

Real-world evidence: the devil is in the detail [PDF]

Diabetologia, 2020
Much has been written about real-world evidence (RWE), a concept that offers an understanding of the effects of healthcare interventions using routine clinical data. The reflection of diverse real-world practices is a double-edged sword that makes RWE attractive but also opens doors to several biases that need to be minimised both in the design and ...
Mugdha, Gokhale, Til, Stürmer, John B, Buse   +2 more
openaire   +2 more sources

Asthma control among treated US asthma patients in Practice Fusion’s electronic medical record research database

npj Primary Care Respiratory Medicine, 2023
This study investigated burden of ‘not well-controlled’ asthma, overall and by Global Initiative for Asthma (GINA) Step, among treated asthma patients in Practice Fusion’s research database.
Jonathan Davitte, Bailey DeBarmore, David Hinds, Shiyuan Zhang, Jessica Chao, Leah Sansbury   +5 more
doaj   +1 more source

Contribution of Real-World Evidence in European Medicines Agency's Regulatory Decision Making [PDF]

, 2023
Real-world data/evidence (RWD/RWE) may provide insightful information on medicines' clinical effects to guide regulatory decisions. While its contribution has been recognized for safety monitoring and disease epidemiology across medicines' life cycles ...
Bakker, Elisabeth, Mol, Peter G. M. ; id_orcid, Carla J. Jonker, Elisabeth Bakker, Peter G. M. Mol, Jonker, Carla J., Viktoriia Starokozhko, Xavier Kurz, Kurz, Xavier, Bakker, Elisabeth; id_orcid, Kelly Plueschke, Plueschke, Kelly, Starokozhko, Viktoriia, Mol, Peter G. M.   +13 more
core   +2 more sources

Disparities in healthcare providers’ interpretations and implementations of ACIP’s meningococcal vaccine recommendations

Human Vaccines & Immunotherapeutics, 2020
Invasive meningococcal disease (IMD) caused by the bacteria Neisseria meningitidis is rare but potentially fatal. For healthy adolescents, the US Advisory Committee on Immunization Practices (ACIP) recommends routine vaccination with MenACWY and ...
Liping Huang, Amir Goren, Lulu K. Lee, Vicky W. Li, Amanda Dempsey, Amit Srivastava   +5 more
doaj   +1 more source

Strategies to Address Current Challenges in Real-World Evidence Generation in Japan

Drugs - Real World Outcomes, 2023
The generation of real-world evidence (RWE), which describes patient characteristics or treatment patterns using real-world data (RWD), is rapidly growing more popular as a tool for decision-making in Japan.
Thomas Laurent, Dimitra Lambrelli, Ryozo Wakabayashi, Takahiro Hirano, Ryohei Kuwatsuru   +4 more
doaj   +1 more source

World Development Indicators 2011 [PDF]

, 2011
World development indicators 2011, the 15th edition in its current format, aims to provide relevant, high-quality, internationally comparable statistics about development and the quality of people's ...
World Bank
core   +1 more source

Real-world Patient Characteristics, Treatment Patterns, Healthcare Resource Utilization and Costs of Commercially-insured US Patients Newly Diagnosed with Major Unipolar Depressive Disorder

, 2022
Further research examining treatment patterns, HCRU, and cost using real-world data can improve understanding of patient experiences in major depressive disorder (MDD) and identify gaps in care.
Grace Stockbower, Yiling Yang, Lia Pizzicato, Richard H. Chapman, Richard Xie, Michael Grabner   +5 more
core   +1 more source

The Disruptive Force of Real-World Evidence

Journal of Clinical Medicine, 2023
Evidence-based medicine was in the past primarily based on the (meta-)analysis of randomized clinical trials (RCTs) [...]
openaire   +3 more sources