Results 61 to 70 of about 1,338,680 (315)

PREVALENCE OF POTENTIAL DRUG-DRUG INTERACTIONS WITH RITONAVIR-CONTAINING COVID-19 MEDICATIONS AMONG THE ADULT PATIENT POPULATION IN AUSTRALIA: ANALYSIS OF PHARMACEUTICAL BENEFITS SCHEME 10% SAMPLE (PBS10) CLAIMS

International Journal of Infectious Diseases, 2023
Intro: Oral antiviral agents with differing modes of action are now available for the treatment of COVID-19. However, potentially life-threatening drug-drug interactions (DDIs) may occur if patients’ underlying co-morbidities are treated with medications
C. Cameron, W.-T. Chen, W.-H. Tan, Y. Chen, C. Lam, E. Igho-Osagie   +5 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Outcomes of patients with COPD switching from multiple-inhaler to once-daily single-inhaler triple therapy in a real-world primary care setting in England: a retrospective pre-post cohort study

BMJ Open Respiratory Research
Background Compared with multiple-inhaler triple therapy (MITT), single-inhaler triple therapy (SITT) with fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) demonstrated improved lung function and meaningful improvements in chronic obstructive ...
Raj Sharma, Claus F Vogelmeier, Kieran J Rothnie, David M G Halpin, Alexandrosz Czira, Chris Compton, Afisi S Ismaila, Robert P Wood, Victoria L Banks, Lucinda J Camidge, Olivia K I Massey, Monica Seif   +11 more
doaj   +1 more source

Emulating RCT Using Asian RWD: DECLARE-TIMI58

, 2022
With the growing amount of clinical evidence derived from large-scale Asian real world data (RWD) and interest in its use in regulatory decision-making, there is a strong need to evaluate the agreement between randomized controlled trials (RCTs) and real
Sohee Park, Ahhyung Choi, Hwa Yeon Ko, Ju-Young Shin, Han Eol Jeong   +4 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

A review of data sharing statements in observational studies published in the BMJ: A cross-sectional study [version 2; referees: 2 approved]

F1000Research, 2017
In order to understand the current state of data sharing in observational research studies, we reviewed data sharing statements of observational studies published in a general medical journal, the British Medical Journal. We found that the majority (63%)
Laura McDonald, Anna Schultze, Alex Simpson, Sophie Graham, Radek Wasiak, Sreeram V. Ramagopalan   +5 more
doaj   +1 more source

Real world evidence: An Indian perspective

Perspectives in Clinical Research, 2016
Randomized controlled trials (RCTs) are the gold standard for measuring the safety and efficacy of drugs. However, they are being challenged by payers and health care providers since they are looking for real world evidence (RWE) to validate whether the new intervention provides similar safety and efficacy as reported in RCT data.
Amit Dang, B N Vallish
openaire   +3 more sources

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

US-England (Flatiron/NCRAS) de Novo mBC Transportability Study Protocol and Statistical Analysis Plan

This study will assess the transportability of real-world evidence from the US to England for individuals diagnosed with de novo metastatic breast cancer based on data from NCRAS and Flatiron Health.
Philani Brian Mpofu, Elspeth Horne, Blythe Adamson, Harlan Pittell, Caitlin Clunie-O'Connor   +4 more
core   +2 more sources

Comparative adherence and persistence of single-inhaler and multiple-inhaler triple therapies among patients with chronic obstructive pulmonary disease in Japan: a retrospective cohort study

BMJ Open
Objectives To evaluate and compare medication adherence and persistence for patients newly initiating single-inhaler triple therapy (SITT) and multiple-inhaler triple therapy (MITT) for chronic obstructive pulmonary disease (COPD) in Japan.Design ...
Olivia Massey, Robert Wood, Kieran J Rothnie, TAKEO ISHII, Alexandrosz Czira, Chris Compton, Afisi Ismaila, Sandra Jokšaitė, Lucinda Camidge, Akiko Mizukami, Masao Yarita, Rad Siddiqui, Thomas Jennison, Kenichi Hashimoto   +13 more
doaj   +1 more source