Results 61 to 70 of about 2,671,764 (310)

STAN: spatio-temporal attention network for pandemic prediction using real-world evidence

J. Am. Medical Informatics Assoc., 2021
Objective We aim to develop a hybrid model for earlier and more accurate predictions for the number of infected cases in pandemics by (1) using patients’ claims data from different counties and states that capture local disease status and medical ...
Junyi Gao, Rakshith Sharma, Cheng Qian, Lucas Glass, J. Spaeder, J. Romberg, Jimeng Sun, Cao Xiao   +7 more
semanticscholar   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Evaluating the Effectiveness of 2024–2025 Seasonal mRNA-1273 Vaccination Against COVID-19-Related Hospitalizations and Medically Attended COVID-19 Among Adults Aged ≥ 18 years in the United States: An Observational Matched Cohort Study

Infectious Diseases and Therapy
Introduction This study evaluated the effectiveness of Moderna’s updated mRNA-1273 vaccine targeting the KP.2 variant, compared to people who did not receive any 2024–2025 COVID-19 vaccine, in preventing COVID-19-associated hospitalizations and medically-
Nevena Vicic, Alina Bogdanov, Zhe Zheng, Taylor Ryan, Ni Zeng, Keya Joshi, Tianyi Lu, Machaon Bonafede, Andre B. Araujo, Amanda Wilson   +9 more
doaj   +1 more source

Real-world evidence for the effectiveness and safety of dupilumab in patients with CRSwNP after 1 year of therapy

The World Allergy Organization Journal, 2023
Objectives For nearly 3 years, the monoclonal antibody dupilumab has been approved in Germany for the treatment of patients with chronic rhinosinusitis with nasal polyps (CRSwNP).
T. Albrecht, Martin M. Sailer, Flavia Capitani, C. van Schaik, H. Löwenheim, S. Becker   +5 more
semanticscholar   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Real-world study of patients with locally advanced HNSCC in the community oncology setting

Frontiers in Oncology, 2023
IntroductionThere is a need to understand the current treatment landscape for LA HNSCC in the real-world setting.MethodsThis retrospective study assessed real-world outcomes and treatment patterns of 1,158 adult patients diagnosed with locally advanced ...
Christopher M. Black, Karthik Ramakrishnan, Eric Nadler, Eric Nadler, Wan-Yu Tseng, Chuck Wentworth, John Murphy, Nicole Fulcher, Liya Wang, Melannie Alexander, Gregory Patton   +10 more
doaj   +1 more source

A Structured Process to Identify Fit‐for‐Purpose Study Design and Data to Generate Valid and Transparent Real‐World Evidence for Regulatory Uses

Clinical pharmacology and therapy, 2023
Generating evidence from real‐world data requires fit‐for‐purpose study design and data. In addition to validity, decision makers require transparency in the reasoning that underlies study design and data source decisions. The 2019 Structured Preapproval
N. Gatto, S. Vititoe, E. Rubinstein, R. Reynolds, U. Campbell   +4 more
semanticscholar   +1 more source

Real world evidence: An Indian perspective

Perspectives in Clinical Research, 2016
Randomized controlled trials (RCTs) are the gold standard for measuring the safety and efficacy of drugs. However, they are being challenged by payers and health care providers since they are looking for real world evidence (RWE) to validate whether the new intervention provides similar safety and efficacy as reported in RCT data.
Amit Dang, B N Vallish
openaire   +3 more sources

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Comorbidities and comedication among individuals in treatment for ADHD: a Danish nationwide study

BMC Psychiatry
Objectives To examine the prevalence of comorbidities and the use of psychiatric comedication among individuals in medical treatment for attention deficit hyperactivity disorder (ADHD), in comparison to a matched control group from the general population.
Maria Vestergaard, Rikke Faergemann Hansen, Per Hove Thomsen, Andreas Hoiberg Bentsen, Anne Cathrine Falch-Joergensen   +4 more
doaj   +1 more source