Results 61 to 70 of about 25,935 (283)

Influence of the stop/start system on CO2 emissions of a diesel vehicle in urban traffic

open access: yes, 2011
This paper presents measurements of CO2 emission and efficiency of stop/start technology on a diesel vehicle in urban traffic. Two four-wheel-drive diesel vehicles with on-board exhaust emission and vehicle activity measurement systems were tested in two
Valdés del Fresno, Manuel   +2 more
core   +1 more source

Assesment of real driving emissions of a bus operating on a dedicated route

open access: yesThermal Science, 2020
The reducing of real driving emissions from public transportation which is using intracity lines has become more important in recent years. This is because the petroleum derived fuel combustion products contributes the global warming as well as adversely the air quality. The fuel consumption perspective is another major economical concern for operating
Özkan, Muammer, Özener, Orkun
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Energy Management Strategies for Extended-Range Electric Vehicles with Real Driving Emission Constraints

open access: yesApplied Sciences
Fuel economy has long been the core control objective in the energy management strategies of extended-range electric vehicles (EREVs), but little research has considered real driving emissions.
Hualong Xu   +6 more
doaj   +1 more source

ParcEMon: IoT Platform for Real-Time Parcel Level Last-Mile Delivery Greenhouse Gas Emissions Reporting and Management

open access: yesSensors, 2022
Transport is Australia’s third-largest source of greenhouse gases accounting for around 17% of emissions. In recent times, and particularly as a result of the global pandemic, the rapid growth within the e-commerce sector has contributed to last-mile ...
Ali Yavari   +7 more
doaj   +1 more source

Real driving emissions data: University of Pretoria

open access: yes, 2022
Real driving emissions (RDE) collected using a Portable Emissions Measurement System (PEMS) unit.This data set includes the RDE records of different vehicles:- Isuzu FTR850 AMT (Road-Rail Vehicle) medium heavy vehicle with a Euro 3 classification (file ...
Joubert, J (via Mendeley Data)
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Real Driving Range in Electric Vehicles: Influence on Fuel Consumption and Carbon Emissions

open access: yesWorld Electric Vehicle Journal, 2021
This paper is focused on the determination of real driving ranges for electric vehicles (EV’s) and how it influences fuel consumption and carbon emissions. A precise method to evaluate the driving range of an EV can establish the correct reduction in GEI
Carlos Armenta-Déu, Erwan Cattin
doaj   +1 more source

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