Results 181 to 190 of about 3,743,885 (328)

ASSESSING RISK FOR STRATEGY FORMULATION IN STEEL INDUSTRY THROUGH REAL OPTION ANALYSIS

, 2011
Farrah Merlinda MUHARAM
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Policy implementations for organic agriculture: A real options approach [PDF]

Organic farming has experienced a vast increase within the EU, despite the fact that it implies greater risk and uncertainty than that of conventional farming.
Alexopoulos, George, Liontakis, Angelos E., Sintori, Alexandra, Tzouramani, Irene   +3 more
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Real Option Analysis for Deep-sea Mineral Resources Development in Japanese Waters

, 2011
Makoto Kohama, Tsuyoshi Adachi, Chiharu Tokoro   +2 more
openalex   +2 more sources

Making real options analysis more accessible for climate change adaptation. An application to afforestation as a flood management measure in the Scottish Borders.

Journal of Environmental Management, 2019
Ruth Dittrich, A. Butler, T. Ball, A. Wreford, D. Moran   +4 more
semanticscholar   +1 more source

Assessing agricultural policy incentives for Greek organic agriculture: A Real options approach [PDF]

The adoption of organic agriculture or livestock involves risk and uncertainty, and to overcome this, well designed schemes are required. Are the current support measures attractive for farmers who wish to convert to organic?
Alexopoulos, George, Liontakis, Angelos E., Sintori, Alexandra, Tzouramani, Irene   +3 more
core   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source

Cost-effective Design of Ringwall Storage Hybrid Power Plants: A Real Options Analysis

, 2014
Sebastian Weibel, Reinhard Madlener
openalex   +1 more source