Results 61 to 70 of about 674,843 (403)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Naive realism and the scientific narration of perception [PDF]

open access: yes, 2018
Naive realism is a widely debated topic in the philosophy of the mind. In this article I will review the theses of naive realism through the works of one of the most influential philosophers who supported and developed them, Michael Martin.
Bucci, Andrea
core  

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Against the pragmatic justification for realism in economic methodology

open access: yesErasmus Journal for Philosophy and Economics, 2011
In recent times, realism in economic methodology has increasingly gained importance. Uskali Mäki and Tony Lawson are the best-known realists within the discipline and even though their approaches are fundamentally different, both provide (among others ...
Simon Deichsel
doaj   +1 more source

The Rise of Realism [PDF]

open access: yes, 2017
A new book by Manuel DeLanda and Graham Harman, The Rise of Realism, is reviewed. The Rise of Realism is an introductory text that aims to clarify the difficulties that surround the philosophical concepts of realism and materialism (as well as their ...
Umbrello, Steven
core   +1 more source

Non-Metaphysical Realism: A Dummett-Inspired Implementation of Putnam’s Internal Realism [PDF]

open access: yes, 2014
The amount of realist positions put forward by philosophers of religion and theologians is impressive. one can certainly doubt whether there is a need for yet another alternative.
Johannesson, Karin
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

A Theory of Genre Formation in the Twentieth Century [PDF]

open access: yes, 2015
In his article "A Theory of Genre Formation in the Twentieth Century" Michael Rodgers explores the relationship between Vladimir Nabokov's Invitation to a Beheading and magical realism in order to theorize about genre formation in the twentieth century ...
Rodgers, Michael
core   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

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