Results 81 to 90 of about 184,647 (356)
The Significance of Being Ethical: An essay on the case for moral realism and theism
Scientia et Fides, 2016 William Irwin defends a form of moral anti-realism, according to which there are no objective moral facts. He contends that moral realism is objectionable because of its being more complex or not as simple as anti-realism; moral realism is in conflict ...
Charles Taliaferro
doaj +1 more source
Structural Realism and the Interpretation of Mathematical Structure
, 2022 Noah Stemeroff
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Evolutionary Debunking, Moral Realism and Moral Knowledge
, 2017 This paper reconstructs what I take to be the central evolutionary debunking argument that underlies recent critiques of moral realism. The argument claims that given the extent of evolutionary influence on our moral faculties, and assuming the truth of ...
R. ShafEr-Landau
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Is Moore’s Moral Objectivist Argument Sufficient Against Moral Relativism?
MarifetnameThis study aims to expose certain weaknesses in Moore’s moral objectivist argument against moral relativism and subjectivism. It suggests that a moral objectivist argument has to explain moral diversity against moral relativism ...
Burhan Başarslan
doaj +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
MAGICAL REALISM-LIKE IN SHAKESPEARE'S A MIDSUMMER NIGHT'S DREAM
Jentera: Jurnal Kajian Sastra, 2018 This article uses concepts of magical realism by Wendy B. Faris to analyze Shakespeare's A Midsummer Night's Dream. We analyze elements of magical realism of the work in mapping discourses between the text and the real life.
Dio Catur Prasetyohadi +2 more
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Basic racial realism, social constructionism, and the ordinary concept of race [PDF]
, 2022 Aaron M. Griffith
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source