Results 31 to 40 of about 18,071 (160)

HIGH PREVALENCE OF JOHN CUNNINGHAM VIRURIA IN RENAL TRANSPLANT RECIPIENTS

open access: yesThe Iraqi Journal of Medical Sciences, 2017
Background: John Cunningham virus (JCV) is one of the important viruses in immunocompromised patients. High JC viruria is seen in kidney allograft recipients; some of them with a polyomavirus associated nephropathy (PVAN) just like BK polyomavirus but to
Mervit B. Jasim   +4 more
doaj   +6 more sources

Loss of Acid Ceramidase in Myeloid Cells Protects From Chronic Colitis in IL10‐Deficient Mice

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Acid ceramidase converts ceramide to sphingosine which can then be converted to sphingosine‐1‐phosphate, a bioactive lipid involved in inflammation. Loss of acid ceramidase in myeloid cells protects from chronic colitis by reducing pro‐inflammatory markers, increasing ceramides, and reducing effector immune cells in the colon.
Keila S. Espinoza   +13 more
wiley   +1 more source

تاثیر تغذیه گلوتامین بر بیان ژن‌های میوژنیک در ماهیچه گوسفند نر زل در شرایط تنش گرمایی [PDF]

open access: yesپژوهش در نشخوارکنندگان
چکیدهسابقه و هدف: در حال حاضر هدف از پرورش گوسفند در ایران تولید گوشت می‌باشد، لذا افزایش تولید در این بخش نیازمند اقداماتی نظیر اصلاح نژاد و همچنین راهکارهای کوتاه مدت نظیر بهبود شرایط بهداشتی و تغذیه‌ای است.
عیسی دیرنده   +3 more
doaj   +1 more source

Rational Engineering of Cellobiose Dehydrogenase via Substrate Pocket Redesign and Electron Transfer Optimization for Efficient Bioelectrosynthesis of Lactobionic Acid

open access: yesChemElectroChem, Volume 13, Issue 20, 16 October 2026.
Structure‐guided substrate‐pocket engineering and electron‐transfer optimization are integrated to enhance cellobiose dehydrogenase for lactose oxidation. The N313D mutation strengthens substrate‐binding interactions, and A165C and W316H improve electron transfer.
Xinyu Cui   +6 more
wiley   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang   +5 more
wiley   +1 more source

Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 10, October 2026.
ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley   +1 more source

Validation of realtime-PCR of Fusarium avenaceum for detection in wheat

open access: yes, 2011
Mould is a common contamination in cereals. The growth of mould can stimulate mycotoxins production andsome of which at critical concentrations cause health problems in humans and animals. Fusarium is one of thefungus species that has been found in crops and can cause major problems for farmers such as reduced harvestand economic losses.
openaire   +2 more sources

Evaluation of a new automated Abbott RealTime MTB RIF/INH assay for qualitative detection of rifampicin/isoniazid resistance in pulmonary and extra-pulmonary clinical samples of Mycobacterium tuberculosis

open access: yesInfection and Drug Resistance, 2017
Pilar Ruiz,1 Manuel Causse,2 Manuel Vaquero,1 Juan Bautista Gutierrez,1,2 Manuel Casal1,2 1Mycobacteria Reference Center, Department of Microbiology, Faculty of Medicine and Nursing, University of Córdoba, Córdoba, Spain; 2Microbiology ...
Ruiz P   +4 more
doaj  

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

open access: yesEnvironmental Toxicology, Volume 41, Issue 10, Page 975-997, October 2026.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei   +6 more
wiley   +1 more source

Real-Time PCR

open access: yesApplied Medical Informatics, 2011
PCR (polymerase chain reaction) is the most important technique in molecular biology. It allows fast and efficient amplification of nucleic acid sequences and isolation of any target sequence.
Cristina DRUGAN   +2 more
doaj  

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