Results 41 to 50 of about 18,071 (160)

Mitochondrial Transplantation Rejuvenates Aging Heart by Restoring Mitophagy Flux via the HIF‐3α‐BNIP3 Axis

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
Aging heart shows mitophagy flux congestion and mitochondrial dysfunction. Aberrant activation of the HIF‐3α‐BNIP3 axis induces mitophagy flux congestion in the aging heart. Mitochondrial transplantation rectifies the HIF‐3α‐BNIP3 axis and restores mitophagy flux by elevating ATP production in the aging heart.
Ning Jin   +13 more
wiley   +1 more source

Prevalence study of Helicobacter pylori infection from normal persons in Thailand

open access: yesJournal of Associated Medical Sciences, 2011
Helicobacter pylori is the most prevalent pathogenic infectious disease found in gastric disorder patients. The new methods to identify H. pylori infection based on molecular technique and immunoassay are beneficial for diagnosis, prognosis and control ...
Piyada Wangroongsarb   +12 more
doaj  

S1‐Leitlinie Tinea capitis

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 10, Page 1510-1524, October 2026.
Zusammenfassung Die unter Federführung der Deutschen Dermatologischen Gesellschaft e. V. (DDG) erstellte S1‐Leitlinie soll Ärzten eine strukturierte Entscheidungsgrundlage für die Versorgung von Patienten mit Tinea capitis bieten und zur Verbesserung der Diagnosesicherheit, Therapieadhärenz und Prävention beitragen.
Peter Mayser   +19 more
wiley   +1 more source

7.ADENOVIRUS INFECTION IN A SAMPLE OF IRAQI KIDNEY TRANSPLANT RECIPIENTS: MOLECULAR AND HEMATOLOGICAL STUDY

open access: yesThe Iraqi Journal of Medical Sciences, 2018
Background: Human Adenovirus (ADV) is one of highly prevalent viruses worldwide, after primary infection, it remains latent and then might reactivate in immunocompromised patients.
Hind M. Ahmed   +4 more
doaj   +6 more sources

Establishment and preliminary evaluation of a non-invasive fetal M blood group genotyping method by real-time PCR

open access: yesZhongguo shuxue zazhi
[Objective] To establish a method for the genotyping of fetal M blood group antigen by extracting cell-free fetal DNA (cff-DNA) from maternal plasma, so as to guide the management of M antigen-negative pregnant women with IgG anti-M antibody during ...
JIA Shuangshuang   +5 more
doaj   +1 more source

Association Between the Root Canal Microbiome and Apical Lesion Size: An Observational Shotgun Metagenomic Study

open access: yesInternational Endodontic Journal, Volume 59, Issue 10, Page 2211-2222, October 2026.
ABSTRACT Aim The aim was to characterize the taxonomic and functional composition of the microbiome involved in primary endodontic infections and to evaluate their association with the periapical lesion size using shotgun metagenomic sequencing. Methodology Samples from primary root canal infections diagnosed with apical periodontitis were analysed ...
Virginia Pérez‐Carrasco   +5 more
wiley   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao   +18 more
wiley   +1 more source

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu   +13 more
wiley   +1 more source

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang   +8 more
wiley   +1 more source

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

open access: yesAdvanced Science, Volume 13, Issue 53, 24 September 2026.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li   +8 more
wiley   +1 more source

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