Results 121 to 130 of about 178,419 (318)
Study of the performance of an oophagous parasitoid Ooencyrtus pityocampae (Mercet) (Hymenoptera: Encyrtidae) to fight against Mediterranean ecosystem pests. Description of the subject.
Tunca, H. +3 more
doaj +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Experiments on raising quality fish seed in floating nurseries and its role in aquaculture in India
Observations on experiments carried out on raising quality fish seed in floating nurseries and raising fish of marketable size in cages at Allahabad are reported.
Natarajan, A. V. +2 more
core
Welfare considerations during incubation and for the first 3 months post- hatching are described for ratite chicks. Welfare of embryos is discussed in the context of the animal being sentient and able to elicit a change in its environment. It is suggested that during development, typical definitions of what constitutes welfare cannot be easily applied ...
openaire +2 more sources
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Rearing the parasitoid Exorista larvarum (L.) on artificial media
The complete development of the tachinid parasitoid Exorista larvarum (L.) was obtained on artificial media both including and devoid of insect components, with adult yields approaching those commonly achieved in the factitious host Galleria mellonella L.
DINDO, MARIA LUISA
core
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Peri-adolescence isolation rearing alters social behavior and nociception in rats
Social isolation results in fundamental behavioral abnormalities in rodents which models certain neuropsychiatric disorders such as schizophrenia. However, the developmental stage that is most vulnerable to social isolation is largely unknown.
Meng, Qingxuan +6 more
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source

