Results 11 to 20 of about 545,522 (315)

Rearranging Detection of Gene Rearrangements [PDF]

Journal of Thoracic Oncology, 2015
®ecent years have witnessed a dramatic expansion in our knowledge of the genetic diversity of non–small-cell lung cancer (NSCLC), and in particular adenocarcinoma. This appreciation of the genetic landscape of the disease has resulted in the development of targeted therapies that are directed to ward activated oncogenes.
Davies, Kurtis D., Doebele, Robert C., Aisner, Dara L.   +2 more
openaire   +2 more sources

Catalytic Stereoselective [2,3]-Rearrangement Reactions

ACS Catalysis, 2015
James Taylor, Andrew David Smith, Kevin Kasten   +2 more
exaly   +2 more sources

Genome Comparisons of the Fission Yeasts Reveal Ancient Collinear Loci Maintained by Natural Selection

Journal of Fungi, 2021
Fission yeasts have a unique life history and exhibit distinct evolutionary patterns from other yeasts. Besides, the species demonstrate stable genome structures despite the relatively fast evolution of their genomic sequences.
Lajos Acs-Szabo, Laszlo Attila Papp, Matthias Sipiczki, Ida Miklos   +3 more
doaj   +1 more source

1-(4-Nitrophenyl)-1H-1,2,3-Triazole-4-carbaldehyde: Scalable Synthesis and Its Use in the Preparation of 1-Alkyl-4-Formyl-1,2,3-triazoles

Organics, 2021
1,2,3-Triazole-4-carbaldehydes are useful synthetic intermediates which may play an important role in the discovery of novel applications of the 1,2,3-triazole moiety.
Tomas Opsomer, Kaat Valkeneers, Ana Ratković, Wim Dehaen   +3 more
doaj   +1 more source

Recent Perspectives on Rearrangement Reactions of Ylides via Carbene Transfer Reactions

Chemistry, 2020
Among the available methods to increase the molecular complexity, sigmatropic rearrangements occupy a distinct position in organic synthesis. Despite being known for over a century sigmatropic rearrangement reactions of ylides via carbene transfer ...
Sripati Jana, Yujing Guo, R. Koenigs
semanticscholar   +1 more source

The Energy Mosaic Austria—A Nationwide Energy and Greenhouse Gas Inventory on Municipal Level as Action Field of Integrated Spatial and Energy Planning

Energies, 2019
While climate agreements are made on an international level, the measures for mitigating climate change must be executed on a local scale. Designing energy and climate related strategies on the level of municipalities has been hampered by the lack of ...
Lore Abart-Heriszt, Susanna Erker, Gernot Stoeglehner   +2 more
doaj   +1 more source

progressiveMauve: Multiple Genome Alignment with Gene Gain, Loss and Rearrangement

PLoS ONE, 2010
Background Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental duplication, gain, and loss can create a mosaic pattern of homology even among closely related organisms.
A. Darling, B. Mau, N. Perna
semanticscholar   +1 more source

Future compatibility of district heating in urban areas — a case study analysis in the context of integrated spatial and energy planning

Energy, Sustainability and Society, 2019
Background District heating is widely used for thermal energy supply and offers a broad range of benefits like the possibility to integrate decentral heat supply technologies or to foster the utilisation of renewable energy sources.
Peter Lichtenwoehrer, Susanna Erker, Franz Zach, Gernot Stoeglehner   +3 more
doaj   +1 more source

Identification of a Novel Pathogenic Rearrangement Variant of the APC Gene Associated with a Variable Spectrum of Familial Cancer

Diagnostics, 2021
Familial adenomatous polyposis (FAP) is an autosomal-dominant condition characterized by the presence of multiple colorectal adenomas, caused by germline variants in the adenomatous polyposis coli (APC) gene.
María Lourdes Garza-Rodríguez, Víctor Treviño, Antonio Alí Pérez-Maya, Hazyadee Frecia Rodríguez-Gutiérrez, Moisés González-Escamilla, Miguel Ángel Elizondo-Riojas, Genaro A. Ramírez-Correa, Oscar Vidal-Gutiérrez, Carlos Horacio Burciaga-Flores, Diana Cristina Pérez-Ibave   +9 more
doaj   +1 more source

Interdisciplinary decision support model for grid-bound heat supply systems in urban areas

Energy, Sustainability and Society, 2019
Background In the past two centuries, energy consumption per capita has significantly increased. At the same time the fundamentals of energy provision have continuously developed towards fossil energy sources.
Susanna Erker, Peter Lichtenwoehrer, Franz Zach, Gernot Stoeglehner   +3 more
doaj   +1 more source