Results 31 to 40 of about 545,522 (315)
Nature Communications, 2017 Osteosarcoma is a primary malignancy of bone that affects children and adults. Here, we present the largest sequencing study of osteosarcoma to date, comprising 112 childhood and adult tumours encompassing all major histological subtypes.
S. Behjati +32 more
semanticscholar +1 more source
High and Variable Rates of Repeat-Mediated Mitochondrial Genome Rearrangement in a Genus of Plants
Molecular biology and evolution, 2018 For 30 years, it has been clear that angiosperm mitochondrial genomes evolve rapidly in sequence arrangement (i.e., synteny), yet absolute rates of rearrangement have not been measured in any plant group, nor is it known how much these rates vary.
L. W. Cole +3 more
semanticscholar +1 more source
Frontiers in Veterinary Science, 2021 Porcine circovirus type 2 (PCV2) belongs to the genus Circovirus of the family Circoviridae, and it has been associated with porcine circovirus (associated) disease (PCVD or PCVAD) in pigs. PCVAD is the generic term for a series of disease syndromes that
Libin Wen +5 more
doaj +1 more source
Polyyne formation via skeletal rearrangement induced by atomic manipulation
Nature Chemistry, 2018 Rearrangements that change the connectivity of a carbon skeleton are often useful in synthesis, but it can be difficult to follow their mechanisms. Scanning probe microscopy can be used to manipulate a skeletal rearrangement at the single-molecule level,
N. Pavliček +7 more
semanticscholar +1 more source
Frontiers in Genetics, 2020 Inverted repeat (IR) regions in the plastomes from land plants induce homologous recombination, generating isomeric plastomes. While the plastomes of Taxaceae species often lose one of the IR regions, considerable isomeric plastomes were created in ...
Yue Zhang +5 more
doaj +1 more source
Life, 2023 Wild upland rice species, including Oryza granulata, possess unique characteristics that distinguish them from other Oryza species. For instance, O. granulata characteristically has a GG genome and is accordingly classified as a basal lineage of the ...
Fen Zhang, Haiqi Kang, Lizhi Gao
doaj +1 more source
Locating rearrangement events in a phylogeny based on highly fragmented assemblies
BMC Genomics, 2016 The inference of genome rearrangement operations requires complete genome assemblies as input data, since a rearrangement can involve an arbitrarily large proportion of one or more chromosomes. Most genome sequence projects, especially those on non-model
Chunfang Zheng, D. Sankoff
semanticscholar +1 more source
AgOTf-catalyzed one-pot reactions of 2-alkynylbenzaldoximes with α,β-unsaturated carbonyl compounds
Beilstein Journal of Organic Chemistry, 2013 AgOTf-catalyzed one-pot reactions of 2-alkynylbenzaldoximes with various α,β-unsaturated carbonyl compounds under mild conditions are described, which provides a facile and efficient pathway for the synthesis of 1-alkylated isoquinoline derivatives.
Qiuping Ding +5 more
doaj +1 more source
Reactions of α-4(20)-epoxy-5-O-mesyltriacetyltaxicine I induced by Bf3·Et2O/Bu4NBr [PDF]
Journal of the Serbian Chemical Society, 2006 The reaction of α-4(20)-epoxy-5-O-mesyltriacetyltaxicine I (2) with BF3·Et2O/Bu4NBr can give rise to 4 different products. Each of these products can be obtained selectively, under the appropriate reaction conditions.
Ferjančić Zorana +3 more
doaj +1 more source
The Curtius Rearrangement: Applications in Modern Drug Discovery and Medicinal Chemistry
ChemMedChem, 2018 The Curtius rearrangement is the thermal decomposition of an acyl azide derived from carboxylic acid to produce an isocyanate as the initial product. The isocyanate can undergo further reactions to provide amines and their derivatives.
Arun K. Ghosh +2 more
semanticscholar +1 more source