Results 51 to 60 of about 354,144 (311)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Beta-selection: abundance of TCRbeta-/gammadelta- CD44- CD25- (DN4) cells in the foetal thymus. [PDF]

open access: yes, 2007
Expression of TCRbeta and pre-TCR signalling are essential for differentiation of CD4- CD8- double negative (DN) thymocytes to the CD4+ CD8+ double-positive (DP) stage.
Outram, Susan V   +9 more
core   +1 more source

Stepwise radical cation Diels–Alder reaction via multiple pathways

open access: yesBeilstein Journal of Organic Chemistry, 2018
Herein we disclose the radical cation Diels–Alder reaction of aryl vinyl ethers by electrocatalysis, which is triggered by an oxidative SET process. The reaction clearly proceeds in a stepwise fashion, which is a rare mechanism in this class.
Ryo Shimizu, Yohei Okada, Kazuhiro Chiba
doaj   +1 more source

Deep Minimum and a Vortex for Positronium Formation in Low-Energy Positron-Helium Collisions

open access: yesAtoms, 2021
We find a zero in the positronium formation scattering amplitude and a deep minimum in the logarithm of the corresponding differential cross section for positron–helium collisions for an energy just above the positronium formation threshold ...
Albandari W. Alrowaily   +2 more
doaj   +1 more source

Rearranging Receptors [PDF]

open access: yesEpilepsia, 2005
Summary: The immature brain is highly susceptible to seizures. The heightened susceptibility to seizures appears to be due, at least in part, to developmental changes that skew the balance between excitatory and inhibitory neurotransmitter systems in the brain in favor of a state of excitation.
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Unidirectional triple and double hydrogen rearrangement reactions in the radical cations of gamma-arylalkanols [PDF]

open access: yes, 1988
Kuck D, Filges U. Unidirectional triple and double hydrogen rearrangement reactions in the radical cations of gamma-arylalkanols. Organic Mass Spectrometry.
Ulrich Filges   +3 more
core   +1 more source

Phylogenetic analysis of endogenous viral elements in the rice genome reveals local chromosomal evolution in Oryza AA-genome species

open access: yesFrontiers in Plant Science, 2023
IntroductionRice genomes contain endogenous viral elements homologous to rice tungro bacilliform virus (RTBV) from the pararetrovirus family Caulimoviridae.
Nozomi Saito   +9 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Assembly and comparative analysis of the complete mitogenome of Rubus chingii var. suavissimus, an exceptional berry plant possessing sweet leaves

open access: yesFrontiers in Plant Science
Rubus chingii var. suavissimus is a special berry plant of Rubus in the Rosaceae family. Its leaves contain high-sweetness, low-calorie, and non-toxic sweet ingredients, known as rubusoside. As a medicine and food biofunctional plant, it is a combination
Yujie Shi   +5 more
doaj   +1 more source

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