Results 51 to 60 of about 239,733 (269)
Cationic cobalt-catalyzed [1,3]-rearrangement of N-alkoxycarbonyloxyanilines
Beilstein Journal of Organic Chemistry, 2018 A cationic cobalt catalyst efficiently promoted the reaction of N-alkoxycarbonyloxyanilines at 30 °C, affording the corresponding ortho-aminophenols in good to high yields.
Itaru Nakamura +3 more
doaj +1 more source
Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate
Molbank, 2017 This note describes a sequence converting an oxime-substituted pyrrolidine into a trisubstituted pyrrole structure. The synthetic route is based on a double chlorination of the pyrrolidine substrate followed by the base induced formation of both an imine
Marcus Baumann, Ian R. Baxendale
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
On an analog of the M.G. Krein theorem for measurable operators
Учёные записки Казанского университета: Серия Физико-математические науки, 2018 Let M be a von Neumann algebra of operators on a Hilbert space H and τ be a faithful normal semifinite trace on M. Let μt(T), t > 0, be a rearrangement of a τ-measurable operator T. Let us consider a τ-measurable operator A, such that μt(A) > 0 for all t
A.M. Bikchentaev
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Rearrangements of dicarba-nido-undecaborates
Тонкие химические технологии, 2011 The thermal and chemically initiated thermal rearrangements of dicarba-nido-undecaborates was explored by computational chemistry. It was shown that the kinetic stability of dianions of these compounds is reduced in the series 2,9 > 7,8 > 1,7 > ...
S. P. Knyazev, A. Yu. Kostiykovitch
doaj
Epilepsia, 2005 Summary: The immature brain is highly susceptible to seizures. The heightened susceptibility to seizures appears to be due, at least in part, to developmental changes that skew the balance between excitatory and inhibitory neurotransmitter systems in the brain in favor of a state of excitation.
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2013 Oxidative cyclization of 6-chloro-4-pyrimidinylhydrazones 4 with iodobenzene diacetate (IBD) in dichloromethane gives rise to [1,2,4]triazolo[4,3-c]pyrimidine derivatives 5a–o.
Caifei Tang, Zhiming Li, Quanrui Wang
doaj +1 more source
Next-Generation Sequencing Technologies for Early-Stage Cutaneous T-Cell Lymphoma
Frontiers in Medicine, 2019 The diagnosis of early stage cutaneous T-cell lymphoma is often difficult, particularly in mycosis fungoides (MF), because the clinical presentation, histological findings, and laboratory findings of MF resemble those of inflammatory skin diseases such ...
Kazuyasu Fujii, Takuro Kanekura
doaj +1 more source