Results 61 to 70 of about 354,144 (311)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Biosynthetic studies on tropic acid and piliformic acid [PDF]

, 1995
This thesis is divided into two parts and covers biosynthetic studies on two secondary metabolites, tropic acid in Part I and piliformic acid, in Part II.(S)-Tropic acid is the acid moiety of the alkaloids hyoscyamine and scopolamine, which are produced ...
Chesters, Nicola C.J.E.
core  

Rearrangement-Free Hydroxylation of Methylcubanes by a Cytochrome P450: The Case for Dynamical Coupling of C–H Abstraction and Rebound

, 2019
The highly strained cubylmethyl radical undergoes one of the fastest radical rearrangements known (reported k = 2.9 × 1010 s–1 at 25 °C) through scission of two bonds of the cube.
Craig M. Williams, Elizabeth H. Krenske (1333482), Elizabeth H. Krenske, G. Paul Savage (152969), Sevan D. Houston, James J. De Voss (7490135), Stephen G. Bell (2271985), James J. De Voss, Md. Raihan Sarkar (3069936), Craig M. Williams (1939036), Stephen G. Bell, Sevan D. Houston (7429049), Md. Raihan Sarkar, G. Paul Savage   +13 more
core   +1 more source

Facile rearrangement of push-pull 5-substituted 4-oxothiazolidines induced by pyridinium hydrobromide perbromide under homogeneous reaction conditions [PDF]

Journal of the Serbian Chemical Society, 2004
Pyridinium hydrobromide perbromide (PHBP) is a highly efficient reagent for the conversion of 5-substituted-2-alkylidene-4-oxothiazolidine derivatives to the corresponding thiazolidines with two fully delocalized exocyclic double bonds at the C(2) and C ...
ZDRAVKO DZAMBASKI, MARIJA BARANAC, RADE MARKOVIC   +2 more
doaj  

A recombination point is conserved in the mitochondrial genome of higher plant species and located downstream from the cox2 pseudogene in Solanum tuberosum L.

Genetics and Molecular Biology, 2006
The potato (Solanum tuberosum L.) mitochondrial cox3/sdh4/pseudo-cox2 gene cluster has previously been identified by heterologous hybridization using a Marchantia polymorpha sdh4 probe.
Susely F.S. Tada, Anete P. Souza
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Dimethylcuprate undergoes a dyotropic rearrangement

, 2010
Comparison of the gas-phase decomposition reactions of [CH3CuCH3]− and [CH3AgCH3]− reveals that [CH3CuCH3]− undergoes a competition between a dyotropic rearrangement and bond homolysis, whilst [CH3AgCH3]− only undergoes bond homolysis.
O'Hair, Richard A. J., Rijs, Nicole J., Yates, Brian F.   +2 more
core   +1 more source

N-cyclopropylimine-1-pyrroline rearrangement. A novel photochemical reaction [PDF]

, 2001
matrix presented A novel aza-(vinylcyclopropane-cyclopentene) photochemical rearrangement is reported. 1-Pyrrolines are easily synthesized in good yields from N-cyclopropylimines. Hydrogen, alkyl, and aryl groups can be placed anywhere within the system,
Campos, P.J. [0000-0002-8917-0318], Rodríguez, M.A. [0000-0003-0123-9905], Sampedro, D. [0000-0003-2772-6453], Soldevilla, A.   +3 more
core   +1 more source

The complete mitochondrial genome of red-fronted parrot (Poicephalus gulielmi) revealed a new gene rearrangement within the order Psittaciformes

Mitochondrial DNA. Part B. Resources, 2017
Vertebrate mitogenomes are thought to be selected for compactness. Therefore, the increasing number of avian mitogenomes comprising duplicated regions is surprising.
Adam Dawid Urantówka, Aleksandra Kroczak, Paweł Mackiewicz   +2 more
doaj   +1 more source