Results 71 to 80 of about 545,522 (315)
Dealing with Difficult Instances of Object Rearrangement
—Rearranging multiple objects is a critical skill for robots so that they can effectively deal with clutter in human spaces. This is a challenging problem as it involves combinatorially large, continuous C-spaces involving multiple movable bodies and ...
A. Krontiris, Kostas E. Bekris
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Rapidity of Genomic Adaptations to Prasinovirus Infection in a Marine Microalga
Prasinoviruses are large dsDNA viruses commonly found in aquatic systems worldwide, where they can infect and lyse unicellular prasinophyte algae such as Ostreococcus.
Sheree Yau +5 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Cationic cobalt-catalyzed [1,3]-rearrangement of N-alkoxycarbonyloxyanilines
A cationic cobalt catalyst efficiently promoted the reaction of N-alkoxycarbonyloxyanilines at 30 °C, affording the corresponding ortho-aminophenols in good to high yields.
Itaru Nakamura +3 more
doaj +1 more source
Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate
This note describes a sequence converting an oxime-substituted pyrrolidine into a trisubstituted pyrrole structure. The synthetic route is based on a double chlorination of the pyrrolidine substrate followed by the base induced formation of both an imine
Marcus Baumann, Ian R. Baxendale
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
On an analog of the M.G. Krein theorem for measurable operators
Let M be a von Neumann algebra of operators on a Hilbert space H and τ be a faithful normal semifinite trace on M. Let μt(T), t > 0, be a rearrangement of a τ-measurable operator T. Let us consider a τ-measurable operator A, such that μt(A) > 0 for all t
A.M. Bikchentaev
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Rearrangements of dicarba-nido-undecaborates
The thermal and chemically initiated thermal rearrangements of dicarba-nido-undecaborates was explored by computational chemistry. It was shown that the kinetic stability of dianions of these compounds is reduced in the series 2,9 > 7,8 > 1,7 > ...
S. P. Knyazev, A. Yu. Kostiykovitch
doaj

