Results 91 to 100 of about 166,784,693 (289)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Specific features of the conflict between elites in the Sverdlovsk Region
Studia Humanitatis, 2013 The Sverdlovsk region is characterized by the difficult and controversial political processes, which require constant monitoring by the scientists. Empirical data collected by the author has let him to analyse the political conflict between Eduard Rossel
Mukhametov Ruslan Salikhovich
doaj
Consequences of Reasoning with Conflicting Obligations
Mind, 2014 Since at least the 1960s, deontic logicians and ethicists have worried about whether there can be normative systems that allow conflicting obligations. Surprisingly, however, little direct attention has been paid to questions about how we may reason with conflicting obligations.
openaire +2 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Pendekatan Kultural sebagai Strategi Resolusi Konflik: Kasus Khon Kaen Thailand
JSP: Jurnal Ilmu Sosial dan Ilmu Politik, 2006 People would not only believe culture as a way of life, but also practicing them for several reasons including for a problem solving method. The assumptions rest on the values that determine people's behavior in their social interaction.
Amelia Maika
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Central Politics and Local Peacemaking : The Conditions for Peace after Communal Conflict
, 2017 Under what conditions can peace be established after violent communal conflict? This question has received limited research attention to date, despite the fact that communal conflicts kill thousands of people each year and often severely disrupt local ...
Elfversson, Emma
core +2 more sources
Conflict of Laws Issues of Bills’ Negotiation in the Law of the United States of America
Московский журнал международного права, 2014 The principles and the order of the settlement of conflict of laws issues of bills’ negotiation in the law of the USA have been researched in this article.
Yuriy S. Kozachuk
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
A behavioural model of choice in the presence of decision conflict [PDF]
, 2014 This paper proposes a model of choice that does not assume completeness of the decision maker’s preferences. The model explains in a natural way, and within a unified framework choice when preference-incomparable options are present, four behavioural ...
Gerasimou, Georgios
core +1 more source