Results 11 to 20 of about 12,605 (160)

Predicting Hotspots for Influenza Virus Reassortment [PDF]

Emerging Infectious Diseases, 2013
The 1957 and 1968 influenza pandemics, each of which killed ≈1 million persons, arose through reassortment events. Influenza virus in humans and domestic animals could reassort and cause another pandemic.
Trevon L. Fuller, Marius Gilbert, Vincent Martin, Julien Cappelle, Parviez Hosseini, Kevin Y. Njabo, Soad Abdel Aziz, Xiangming Xiao, Peter Daszak, Thomas B. Smith   +9 more
doaj   +4 more sources

New approaches for unravelling reassortment pathways [PDF]

BMC Evolutionary Biology, 2013
Background Every year the human population encounters epidemic outbreaks of influenza, and history reveals recurring pandemics that have had devastating consequences.
Svinti Victoria, Cotton James A, McInerney James O   +2 more
doaj   +3 more sources

TreeKnit: Inferring ancestral reassortment graphs of influenza viruses. [PDF]

PLoS Computational Biology, 2022
When two influenza viruses co-infect the same cell, they can exchange genome segments in a process known as reassortment. Reassortment is an important source of genetic diversity and is known to have been involved in the emergence of most pandemic ...
Pierre Barrat-Charlaix, Timothy G Vaughan, Richard A Neher   +2 more
doaj   +7 more sources

Pathogenesis and Transmission of a Reassorted H1 Influenza A Virus Detected in North American Swine. [PDF]

Influenza Other Respir Viruses
ABSTRACT Background The USDA influenza A virus in swine national surveillance plan identified an increase in the detection frequency of a group of swine 1A.1.1.3 hemagglutinin (HA) clade viruses. This change was associated with reassortment events that resulted in new neuraminidase (NA) gene pairings.
Goulart DB, Souza CK, Zanella GC, Snyder CA, Zanella JC, Markin A, Arruda B, Anderson TK, Baker AL.   +8 more
europepmc   +2 more sources

Development of reassortant influenza vaccines: classical reassortment or reverse genetics?

Russian Journal of Infection and Immunity, 2023
An important feature of influenza vaccines, which distinguishes them from other immunobiological preparations, is that they have no fixed composition. Due to the constant influenza virus antigenic variability, production facilities require timely supply with relevant vaccine strains undoable due to the lack of proper method for the convenient, rapid ...
Irina V. Kiseleva, Larisa G. Rudenko
openaire   +1 more source

Molecular Epidemiology and Genetic Diversity of Influenza B Viruses Based on Whole-Genome Analysis in Japan and Myanmar, 2016-2020. [PDF]

Influenza Other Respir Viruses
ABSTRACT Background Influenza B virus (IBV) contributes to seasonal epidemics, but its molecular evolution is less defined than influenza A. We analyzed IBVs collected in Japan and Myanmar (2016–2020) to investigate lineage dynamics, reassortment, and genetic mismatch with vaccine strains. Methods Respiratory specimens from patients with influenza‐like
Ichikawa Y, Saito R, Chon I, Phyu WW, Kyaw Y, Win SMK, Japanese Influenza Collaborative Study Group, Yoshioka S, Sun Y, Li J, Purnama TB, Wagatsuma K, Tamura T, Watanabe H, Aye MM, Setk S, Tin HH.   +16 more
europepmc   +2 more sources

Frequency of influenza H3N2 intra-subtype reassortment: attributes and implications of reassortant spread [PDF]

BMC Biology, 2016
De plus en plus de preuves suggèrent que le réassortiment de la grippe contribue non seulement à l'émergence de nouvelles pandémies humaines, mais joue également un rôle important dans les épidémies de grippe saisonnière, la gravité de la maladie, l'évolution et l'efficacité des vaccins.
Irina Maljkovic Berry, Melanie C. Melendrez, Tao Li, Anthony W. Hawksworth, Gary T. Brice, Patrick J. Blair, Eric S. Halsey, Maya Williams, Stefan Fernandez, In‐Kyu Yoon, Leslie Edwards, Robert A. Kuschner, Xiangui Lin, Stephen J. Thomas, Richard G. Jarman   +14 more
openaire   +2 more sources

Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and Gulls

Viruses, 2021
Influenza A viruses (IAVs) evolve via point mutations and reassortment of viral gene segments. The patterns of reassortment in different host species differ considerably.
Yulia Postnikova, Anastasia Treshchalina, Elizaveta Boravleva, Alexandra Gambaryan, Aydar Ishmukhametov, Mikhail Matrosovich, Ron A. M. Fouchier, Galina Sadykova, Alexey Prilipov, Natalia Lomakina   +9 more
doaj   +1 more source

HopPER: an adaptive model for probability estimation of influenza reassortment through host prediction

BMC Medical Genomics, 2020
Background Influenza reassortment, a mechanism where influenza viruses exchange their RNA segments by co-infecting a single cell, has been implicated in several major pandemics since 19th century.
Rui Yin, Xinrui Zhou, Shamima Rashid, Chee Keong Kwoh   +3 more
doaj   +1 more source

Neuraminidase and hemagglutinin matching patterns of a highly pathogenic avian and two pandemic H1N1 influenza A viruses. [PDF]

PLoS ONE, 2010
BACKGROUND: Influenza A virus displays strong reassortment characteristics, which enable it to achieve adaptation in human infection. Surveying the reassortment and virulence of novel viruses is important in the prevention and control of an influenza ...
Yonghui Zhang, Xiaojing Lin, Guoqin Wang, Jianfang Zhou, Jian Lu, Honglan Zhao, Fengwei Zhang, Jia Wu, Chunqiong Xu, Ning Du, Zi Li, Ye Zhang, Xiaoyi Wang, Shengli Bi, Yuelong Shu, Hongning Zhou, Wenjie Tan, Xiaobing Wu, Zhihui Chen, Yue Wang   +19 more
doaj   +1 more source