Results 21 to 30 of about 2,128 (154)
Frontiers in Allergy, 2021 Asthma is associated with increased deposition and altered phenotype of airway smooth muscle (ASM) cells. However, little is known about the processes responsible for these changes. It has been suggested that alterations of the extracellular matrix (ECM)
Selma Ben Hamouda +4 more
doaj +1 more source
Recent Advances in Liver Engineering With Decellularized Scaffold
Frontiers in Bioengineering and Biotechnology, 2022 Liver transplantation is currently the only effective treatment for patients with end-stage liver disease; however, donor liver scarcity is a notable concern. As a result, extensive endeavors have been made to diversify the source of donor livers.
Qingqing Dai +6 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 Introduction: Despite progress in whole-organ decellularization and recellularization, maintaining long-term perfusion in vivo remains a hurdle to realizing clinical translation of bioengineered kidney grafts. The objectives for the present study were to
Joseph S. Uzarski +10 more
doaj +1 more source
Recellularization of auricular cartilage via elastase-generated channels [PDF]
Biofabrication, 2019 Decellularized tissue matrices are promising substrates for tissue generation by stem cells to replace poorly regenerating tissues such as cartilage. However, the dense matrix of decellularized cartilage impedes colonisation by stem cells. Here, we show that digestion of elastin fibre bundles traversing auricular cartilage creates channels through ...
J Lehmann +8 more
openaire +3 more sources
Cells, 2021 Background. Liver transplantation remains the only viable therapy for liver failure but has a severely restricted utility. Here, we aimed to decellularize rat livers to form acellular 3D bio-scaffolds suitable for seeding with induced pluripotent cells ...
Nesrine Ebrahim +19 more
doaj +1 more source
Decellularized Periodontal Ligament Cell Sheets with Recellularization Potential [PDF]
Journal of Dental Research, 2014 The periodontal ligament is the key tissue facilitating periodontal regeneration. This study aimed to fabricate decellularized human periodontal ligament cell sheets for subsequent periodontal tissue engineering applications. The decellularization protocol involved the transfer of intact human periodontal ligament cell sheets onto melt electrospun ...
Farag, A. +5 more
openaire +3 more sources
Recellularization of decellularized porcine caval veins
Biomedical Science and Engineering, 2021 Decellularized material has been reported to be more suitable for cells to grow when compared to synthetic materials because repopulating cells are provided with the structural environment of native tissue. The aim of this study is to prepare and to test porcine caval veins through their decellularization followed by repopulation with human endothelial
Maria Stefania Massaro +8 more
openaire +2 more sources
Decellularization and Recellularization Methodology for Human Saphenous Veins [PDF]
Journal of Visualized Experiments, 2018 Vascular conduits used during most vascular surgeries are allogeneic or synthetic grafts that often lead to complications caused by immunosuppression and poor patency. Tissue engineering offers a novel solution to generate personalized grafts with a natural extracellular matrix containing the recipient's cells using the method of decellularization and ...
Kumar Kuna, Vijay +2 more
openaire +2 more sources
EXPERIENCE OF PERFUSION RECELLULARIZATION OF BIOLOGICAL LUNG SCAFFOLD IN RATS
Вестник трансплантологии и искусственных органов, 2016 Aim. The main aim of our research is to evaluate the process of rat lung decellularization and recellularization as the initial step of tissue-engineered organs creation.Materials and methods.
E. V. Kuevda +8 more
doaj +1 more source
Uterus bioengineering as a future alternative to uterus transplantation
Clinical and Experimental Obstetrics & Gynecology, 2022 Objective: To review the current knowledge on uterus bioengineering and discuss potential future directives. Uterus bioengineering may solve two major hurdles in organ transplantation of a uterus, organ shortage and control of rejection by ...
Arvind Manikantan Padma +2 more
doaj +1 more source