Recent Advances in Liver Engineering With Decellularized Scaffold
Frontiers in Bioengineering and Biotechnology, 2022 Liver transplantation is currently the only effective treatment for patients with end-stage liver disease; however, donor liver scarcity is a notable concern. As a result, extensive endeavors have been made to diversify the source of donor livers.
Qingqing Dai +6 more
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Frontiers in Bioengineering and Biotechnology, 2023 Introduction: Despite progress in whole-organ decellularization and recellularization, maintaining long-term perfusion in vivo remains a hurdle to realizing clinical translation of bioengineered kidney grafts. The objectives for the present study were to
Joseph S. Uzarski +10 more
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Guided Tissue Regeneration in Heart Valve Replacement: From Preclinical Research to First-in-Human Trials [PDF]
, 2015 Heart valve tissue-guided regeneration aims to offer a functional and viable alternative to current prosthetic replacements. Not requiring previous cell seeding and conditioning in bioreactors, such exceptional tissue engineering approach is a very ...
Gerosa, Gino, Iop, Laura
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Tissue engineering by decellularization and 3D bioprinting [PDF]
, 2017 Discarded human donor organs have been shown to provide decellularized extracellular matrix (dECM) scaffolds suitable for organ engineering. The quest for appropriate cell sources to satisfy the need of multiple cells types in order to fully repopulate ...
Campistol Plana, Josep M. +8 more
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EXPERIENCE OF PERFUSION RECELLULARIZATION OF BIOLOGICAL LUNG SCAFFOLD IN RATS
Вестник трансплантологии и искусственных органов, 2016 Aim. The main aim of our research is to evaluate the process of rat lung decellularization and recellularization as the initial step of tissue-engineered organs creation.Materials and methods.
E. V. Kuevda +8 more
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Recellularization of Native Tissue Derived Acellular Scaffolds with Mesenchymal Stem Cells
Cells, 2021 The functionalization of decellularized scaffolds is still challenging because of the recellularization-related limitations, including the finding of the most optimal kind of cell(s) and the best way to control their distribution within the scaffolds to ...
Ebtehal Ahmed, Tarek Saleh, Meifeng Xu
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Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans [PDF]
, 2017 Decellularization of pancreata and repopulation of these non-immunogenic matrices with islets and endothelial cells could provide transplantable, endocrine Neo- Pancreata.
Andreou, A. +19 more
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Developing Regenerative Treatments for Developmental Defects, Injuries, and Diseases Using Extracellular Matrix Collagen-Targeting Peptides. [PDF]
, 2019 Collagen is the most widespread extracellular matrix (ECM) protein in the body and is important in maintaining the functionality of organs and tissues.
Goldbloom-Helzner, Leora +2 more
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Bioengineering, 2023 Biomaterial templates play a critical role in establishing and bioinstructing three-dimensional cellular growth, proliferation and spatial morphogenetic processes that culminate in the development of physiologically relevant in vitro liver models ...
Tanveer Ahmed Mir +11 more
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Lung bioengineering: physical stimuli and stem/progenitor cell biology interplay towards biofabricating a functional organ [PDF]
, 2016 A current approach to obtain bioengineered lungs as a future alternative for transplantation is based on seeding stem cells on decellularized lung scaffolds.
Campillo, Noelia +5 more
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