Sterilization of lung matrices by supercritical carbon dioxide [PDF]
, 2016 Lung engineering is a potential alternative to transplantation for patients with end-stage pulmonary failure. Two challenges critical to the successful development of an engineered lung developed from a decellularized scaffold include (i) the suppression
Balestrini, Jenna L +10 more
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Uterus bioengineering as a future alternative to uterus transplantation
Clinical and Experimental Obstetrics & Gynecology, 2022 Objective: To review the current knowledge on uterus bioengineering and discuss potential future directives. Uterus bioengineering may solve two major hurdles in organ transplantation of a uterus, organ shortage and control of rejection by ...
Arvind Manikantan Padma +2 more
doaj +1 more source
Porous Decellularized Nerve Grafts Facilitate Recellularization and Nerve Regeneration in a Rat Model of Critical Long-Gap Peripheral Nerve Injury. [PDF]
Adv Healthc MaterA decellularized nerve graft (DNG) is modified to generate a porous DNG (PDNG). The PDNG is used to repair a 30‐mm peripheral nerve injury (PNI) defect, and is compared with isograft, serving as the standard, and DNG, a widely used alternative. The result shows that PDNG facilitated nerve regeneration in long‐gap PNI, evidenced by better‐aligned axonal
Alimi OA +10 more
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Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells [PDF]
, 2016 Considerable progress has been made in recent years toward elucidating the correlation among nanoscale topography, mechanical properties, and biological behavior of cardiac valve substitutes.
Aguiari, Paola +11 more
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Lung Microvascular Niche, Repair, and Engineering
Frontiers in Bioengineering and Biotechnology, 2020 Biomaterials have been used for a long time in the field of medicine. Since the success of “tissue engineering” pioneered by Langer and Vacanti in 1993, tissue engineering studies have advanced from simple tissue generation to whole organ generation with
Tomoshi Tsuchiya +5 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Reproduction of different tissues using scaffolds and materials is a major element in regenerative medicine. The regeneration of whole organs with decellularized extracellular matrix (dECM) has remained a goal despite the use of these materials for ...
Afarin Neishabouri +5 more
doaj +1 more source
Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans [PDF]
, 2019 Introduction: Decellularization of pancreata and repopulation of these non-immunogenic matrices with islets and endothelial cells could provide transplantable, endocrine Neo-Pancreata.
Napierala, Hendrik
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Decellularization and Recellularization Technologies in Tissue Engineering
Cell Transplantation, 2014 Decellularization is the process by which cells are discharged from tissues/organs, but all of the essential cues for cell preservation and homeostasis are retained in a three-dimensional structure of the organ and its extracellular matrix components ...
Ru-Huei Fu Ph.D. +13 more
doaj +1 more source
Preparation and Use of Decellularized Extracellular Matrix for Tissue Engineering
Journal of Functional Biomaterials, 2022 The multidisciplinary fields of tissue engineering and regenerative medicine have the potential to revolutionize the practise of medicine through the abilities to repair, regenerate, or replace tissues and organs with functional engineered constructs. To
Adam D. McInnes +2 more
doaj +1 more source
The Host Immune Response to Tissue-Engineered Organs: Current Problems and Future Directions [PDF]
, 2016 As the global health burden of chronic disease increases, end-stage organ failure has become a costly and intractable problem. De novo organ creation is one of the long-term goals of the medical community.
Birchall, MA +3 more
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