Results 51 to 60 of about 4,532 (195)

Amyloid persistence in decellularized liver: biochemical and histopathological characterization [PDF]

, 2015
Systemic amyloidoses are a group of debilitating and often fatal diseases in which fibrillar protein aggregates are deposited in the extracellular spaces of a range of tissues.
Al-Akkad, W, Al-Shawi, R, Bellotti, V, De Coppi, P, Dhar, D, Ellmerich, S, Gilbertson, JA, Giorgetti, S, Hall, AR, Hawkins, PN, Mangione, PP, Mazza, G, Pinzani, M, Simons, JP, Taylor, GW, Urbani, L   +15 more
core   +1 more source

Regenerative strategies for kidney engineering [PDF]

, 2016
The kidney is the most important organ for water homeostasis and waste excretion. It performs several important physiological functions for homeostasis: it filters the metabolic waste out of circulation, regulates body fluid balances, and acts as an ...
Garreta, Elena, Izpisúa Belmonte, Juan Carlos, Montserrat, Núria   +2 more
core   +1 more source

Decellularized scaffold of cryopreserved rat kidney retains its recellularization potential. [PDF]

PLoS ONE, 2017
The multi-cellular nature of renal tissue makes it the most challenging organ for regeneration. Therefore, till date whole organ transplantations remain the definitive treatment for the end stage renal disease (ESRD). The shortage of available organs for
Baldeep Chani, Veena Puri, Ranbir C Sobti, Vivekanand Jha, Sanjeev Puri   +4 more
doaj   +1 more source

A REVIEW OF CELLULARIZATION STRATEGIES FOR TISSUE ENGINEERING OF WHOLE ORGANS

Frontiers in Bioengineering and Biotechnology, 2015
With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for organ engineering were generated from numerous tissues, including the heart, lung, liver, kidney and pancreas, for use as alternatives to traditional organ ...
Michelle E Scarritt, Nicholas C Pashos, Bruce Alan Bunnell   +2 more
doaj   +1 more source

In vivo recellularization of xenogeneic vascular grafts decellularized with high hydrostatic pressure method in a porcine carotid arterial interpose model.

PLoS ONE, 2021
Autologous vascular grafts are widely used in revascularization surgeries for small caliber targets. However, the availability of autologous conduits might be limited due to prior surgeries or the quality of vessels.
Shunji Kurokawa, Yoshihide Hashimoto, Seiichi Funamoto, Kozue Murata, Akitatsu Yamashita, Kazuhiro Yamazaki, Tadashi Ikeda, Kenji Minatoya, Akio Kishida, Hidetoshi Masumoto   +9 more
doaj   +1 more source

A novel ex vivo lung cancer model based on bioengineered rat lungs

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Two-dimensional cell cultures have contributed substantially to lung cancer research, but 3D cultures are gaining attention as a new, more efficient, and effective research model.
Satoshi Mizoguchi, Tomoshi Tsuchiya, Tomoshi Tsuchiya, Ryoichiro Doi, Tomohiro Obata, Mayumi Iwatake, Shintaro Hashimoto, Hirotaka Matsumoto, Hiroshi Yukawa, Hiroko Hayashi, Tao-Sheng Li, Kazuko Yamamoto, Keitaro Matsumoto, Takuro Miyazaki, Koichi Tomoshige, Takeshi Nagayasu   +15 more
doaj   +1 more source

A dynamic distention protocol for whole-organ bladder decellularization: histological and biomechanical characterization of the acellular matrix [PDF]

, 2016
A combined physical\u2013chemical protocol for whole full-thickness bladder decellularization is proposed, based on organ cyclic distention through repeated infusion/withdrawal of the decellularization agents through the urethra.
F. Acocella, F. Consolo, F. Riva, G. Tremolada, G.B. Fiore, M. Soncini, S. Brizzola, V. Grieco   +7 more
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Tissue engineered uterine tissue supports pregnancy in a rat model [PDF]

, 2017
Background: Absolute uterine factor infertility affects about 1:500 women in fertile age. This can now be cured by uterus transplantation, a procedure that involves risky donor surgery and side effects of immunosuppression.
Bandstein, Sara
core  

Macrophage‐targeted cerium‐tannic acid metal‐polyphenol framework nanoenzyme promotes in situ heart valves regeneration through adaptive immunomodulation

BMEMat, EarlyView.
A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song, Yunlong Wu, Xing Chen, Yafei Liu, Mengna Dong, Jiawei Shi, Xichi Wang, Nianguo Dong, Weihua Qiao, Qin Wang   +9 more
wiley   +1 more source