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Splicing heterogeneity: separating signal from noise
Single-cell analyses have revealed a tremendous variety among cells in the abundance and chemical composition of RNA. Much of this heterogeneity is due to alternative splicing by the spliceosome.
Yihan Wan, Daniel R. Larson
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Background The human pancreas is composed of specialized cell types producing hormones and enzymes critical to human health. These specialized functions are the result of cell type-specific transcriptional programs which manifest in cell-specific gene ...
David Sturgill, Li Wang, H. Efsun Arda
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Effect of Receptor-Destroying Enzyme on the Growth of EMC Virus in Tissue Culture [PDF]
Helen Kodza, C. W. Jungeblut
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A Receptor-Destroying Enzyme in Human Saliva and Its Possible Relation to Poliomyelitis Infection [PDF]
B. Hofman
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TET-Catalyzed 5-Carboxylcytosine Promotes CTCF Binding to Suboptimal Sequences Genome-wide
Summary: The mechanisms supporting dynamic regulation of CTCF-binding sites remain poorly understood. Here we describe the TET-catalyzed 5-methylcytosine derivative, 5-carboxylcytosine (5caC), as a factor driving new CTCF binding within genomic DNA ...
Kyster K. Nanan+6 more
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INHIBITORY INTERACTION OF RECEPTOR UNITS IN THE EYE OF LIMULUS [PDF]
H. K. Hartline, Floyd Ratliff
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Structures of adenosine receptor A2BR bound to endogenous and synthetic agonists
Hongmin Cai+12 more
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One of the major hurdles for cancer immunotherapy is the host’s innate antiviral defense mechanisms. They include innate immune cells, such as natural killer (NK) cells and macrophages, which can be recruited within hours to the site of injection to ...
Xinping Fu+3 more
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SPATIAL SUMMATION OF INHIBITORY INFLUENCES IN THE EYE OF LIMULUS, AND THE MUTUAL INTERACTION OF RECEPTOR UNITS [PDF]
H. K. Hartline, Floyd Ratliff
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