Results 151 to 160 of about 119,693 (290)

Potential differences in receptor‐mediated G‐protein activation in postmortem human hippocampal membranes prepared from healthy controls and suicide victims

Neuropsychopharmacology Reports
Aim Postmortem brain studies offer enormous opportunities to study molecular mechanisms associated with suicide. In the present study, conventional [35S]GTPγS binding assay and its version‐up method ([35S]GTPγS binding/immunoprecipitation assay) were ...
Yuji Odagaki, Masakazu Kinoshita, Miklós Palkovits, Dasiel Oscar Borroto‐Escuela, Kjell Fuxe   +4 more
doaj   +1 more source

Genome‐Wide Association Study of Atrial Fibrillation Recurrence After Radiofrequency Catheter Ablation in a Japanese Population

Journal of Cardiovascular Electrophysiology, EarlyView.
This study aimed to identify the factors associated with atrial fibrillation (AF) recurrence after catheter ablation. The clinical information analysis revealed persistent AF, nonpulmonary AF triggers, NT‐proBNP levels, and the left atrial volume were clinical predictors of recurrence.
Takumi Sakai, Motoki Furutani, Mika Nakashima, Naoki Ishibashi, Junji Maeda, Naoto Oguri, Shogo Miyamoto, Shunsuke Miyauchi, Sho Okamura, Yousaku Okubo, Takehito Tokuyama, Noboru Oda, Risa Mitsumori, Shumpei Niida, Kouichi Ozaki, Daichi Shigemizu, Yukiko Nakano   +16 more
wiley   +1 more source

Interaksi Teofilin Ekstrak Daun Teh (Camellia sinensis ) dengan Adenosine A1 receptor dalam Menghambat Penyakit Asma [PDF]

Penelitian ini bertujuan untuk mengeksplorasi potensi interaksi teofilin yang diekstraksi dari daun teh (Camellia sinensis) dengan Adenosine A1 receptor dalam upaya menghambat penyakit asma.
Suryani, Okta, Verawati, Rismi
core   +1 more source

Structure of the Adenosine A1 Receptor Reveals the Basis for Subtype Selectivity

Cell, 2017
A. Glukhova, D. Thal, A. T. Nguyen, E. A. Vecchio, M. Jörg, P. Scammells, L. May, P. Sexton, A. Christopoulos   +8 more
semanticscholar   +1 more source

Modulation of Sodium and Ammonia Transporters in the Context of Viral Gill Diseases in Common Carp (Cyprinus carpio)

Journal of Fish Diseases, EarlyView.
ABSTRACT Osmoregulation and ammonia removal are among key physiological processes that take place in gills and affect fish homeostasis and well‐being. These processes can be disrupted by numerous environmental factors, but also by viral infections, especially those leading to severe gill disorders.
Maria Zawisza, Muhammad Abdullah, Magdalena Marcinkowska, Marek Matras, Krzysztof Rakus, Mikolaj Adamek   +5 more
wiley   +1 more source

N3-substituted xanthines as irreversible adenosine receptor antagonists

, 2000
8-Cyclopentyl-3-(3-(4-fluorosulfonylbenzoyl)oxy)propyl-propylxanthine (44, FSCPX) has been reported to exhibit potent and selective irreversible antagonism of the A1 adenosine receptor when using in vitro biological preparations.
Beauglehole, Anthony Robert.
core  

Adenosine A1 receptor activation attenuates cardiac hypertrophy and fibrosis in response to α1‐adrenoceptor stimulation in vivo

British Journal of Pharmacology, 2015
S. Puhl, A. Kazakov, A. Müller, Peter Fries, D. Wagner, M. Böhm, Christoph Maack, Y. Devaux   +7 more
semanticscholar   +1 more source

Refuting a Temporal Correlation: Interictal Epileptic Discharges Do Not Preferentially Occur During Respiratory Events in Patients With Sleep‐Related Breathing Disorder and Epilepsy

Journal of Sleep Research, EarlyView.
ABSTRACT The bidirectional interaction between sleep and epilepsy is well known. In particular, it has been established that sleep apnea can worsen epilepsy, whereas sleep apnea (SA) treatment has a beneficial effect on seizure control. However, the exact mechanisms whereby SA promotes epileptic seizures are unknown.
Christian M. Horvath, Hristina Drangova, Jakub Stefela, Carolin Schäfer, Frederic Zubler   +4 more
wiley   +1 more source

Creatine, similarly to ketamine, affords antidepressant-like effects in the tail suspension test via adenosine A1 and A2A receptor activation

Purinergic Signalling Purinergic Signalling, 2015
M. Cunha, F. L. Pazini, Julia M. Rosa, A. B. Ramos-Hryb, A. Oliveira, M. Kaster, A. Rodrigues   +6 more
semanticscholar   +1 more source

Dreaming of Better Treatments: Advances in Drug Development for Sleep Medicine and Chronotherapy

Journal of Sleep Research, EarlyView.
ABSTRACT Throughout history, the development of new sleep medicines has been driven by progress in our understanding of the mechanisms underlying sleep. Ancient civilisations used their understanding of the sedative nature of natural herbs and compounds to induce sleep.
Brooke A. Prakash, Ishani Shah, Guohao Ni, Sridhar Vasudevan, Aarti Jagannath, Russell G. Foster   +5 more
wiley   +1 more source