Results 41 to 50 of about 74,938 (266)
陆军军医大学学报Objective To explore the expression profile of adenosine A1 receptor in the paraventricular thalamic nucleus (PVT) in wakefulness/sleep state and its role in regulating sleep.
ZHU Yifeng, WANG Na, HU Junya
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On the basis of sex: male vs. female rat adenosine A1/A2A receptor affinity
BMC Research Notes, 2023 Objective To ensure reproducibility in biomedical research, the biological variable sex must be reported; yet a reason for using male (instead of female) rodents is seldom given.
Helena D. Janse van Rensburg +2 more
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Frontiers in Pharmacology, 2016 Both adenosine A1 receptor and cGMP inhibit synaptic transmission at the hippocampus and recently it was found that A1 receptor increased cGMP levels in hippocampus, but the role of cGMP on A1 receptor-mediated inhibition of synaptic transmission remains
Isa ePinto +5 more
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Calcium-independent inhibitory G-protein signaling induces persistent presynaptic muting of hippocampal synapses [PDF]
, 2011 Adaptive forms of synaptic plasticity that reduce excitatory synaptic transmission in response to prolonged increases in neuronal activity may prevent runaway positive feedback in neuronal circuits.
Chang, Chun Yun +3 more
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Neural Regeneration Research, 2017 The activation of adenosine A1 receptors is important for protecting against ischemic brain injury and pretreatment with electroacupuncture has been shown to mitigate ischemic brain insult.
Qin-xue Dai +7 more
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Anticonvulsant activity of B2, an adenosine analog, on chemical convulsant-induced seizures. [PDF]
PLoS ONE, 2013 Epilepsy is a chronic neurological disorder characterized by recurrent seizures. However, approximately one-third of epilepsy patients still suffer from uncontrolled seizures. Effective treatments for epilepsy are yet to be developed. N (6)-(3-methoxyl-4-
Min Li +4 more
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The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Central adenosinergic system and its clinical importance
Psychiatry and Clinical Psychopharmacology, 2021 Adenosine is a neuromodulator widely distributed throughout the body. Since it is continuously synthesized, it can be concluded that there is a basal adenosinergic tonus, which has inhibitory effects in general.
Hakan Kayır, I. Tayfun Uzbay
doaj
Molecules, 2012 This study was undertaken in order to investigate the effect of chronic treatment with 5′-chloro-5′-deoxy-(±)-ENBA, a potent and highly selective agonist of human adenosine A1 receptor, on thermal hyperalgesia and mechanical ...
Livio Luongo +10 more
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Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury [PDF]
, 2005 Acute respiratory distress syndrome (ARDS) usually requires symptomatic supportive therapy by intubation and mechanical ventilation with the supplemental use of high oxygen concentrations.
+62 more
core +5 more sources