Results 61 to 70 of about 21,687 (230)

Endocannabinoid Release Modulates Electrical Coupling between CCK Cells Connected via Chemical and Electrical Synapses in CA1.

, 2011
Electrical coupling between some subclasses of interneurons is thought to promote coordinated firing that generates rhythmic synchronous activity in cortical regions.
Ali eAfia, Jonathan eIball, Afia B. Ali, Jonathan Iball, Iball, J, Ali, AB   +5 more
core   +1 more source

Is a Single Nucleotide Polymorphism Marker in the Cholecystokinin A Receptor Gene Practically Suitable for Improving the Growth Traits of Hinai-jidori Chickens?

The Journal of Poultry Science, 2020
We have previously reported a significant association between the single-nucleotide polymorphism (SNP; g.420 C>A) in the cholecystokinin type A receptor gene (CCKAR) and the growth traits of Hinai-dori, a breed of chicken that is indigenous to Japan ...
Kazuhiro Rikimaru, Yuki Sato, Yukari Ito, Shiori Fukuda, Senetsu Sasaki, Hideaki Takahashi   +5 more
doaj   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system

The FEBS Journal, EarlyView.
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger, Alice Wiedmann, Rayan Hassan M. Elshikhidriss, Thomas Brunner   +3 more
wiley   +1 more source

Biochemical Characterization of a Subtype Pancreatic Cholecystokinin Receptor and of its Agonist Binding Domain

, 2008
International audienceThis study was undertaken in order to improve photoaffinity labelling efficiency of pancreatic cholecystokinin receptor by the cleavable probe 125I-ASD-(Thr28,Ahx31)-CCK-25-33 and to further characterize the denaturated receptor and
Jiménez, Juan, Poirot, Sandrine Silvente, Vaysse, Nicole, Dufresne, Marlène, Fourmy, Daniel   +4 more
core   +1 more source

Cholecystokinin receptor antagonist challenge elicits brain-wide functional connectome modulation with micronetwork hippocampal decreased calcium transients

, 2023
The cortical distribution and functional role of cholecystokinin (CCK) are largely unknown. Here, a CCK receptor antagonist challenge paradigm was developed to assess functional connectivity and neuronal responses.
Ziqi An, Liu, JM, Francis A M Manno, Jiaming Liu, He, JF, Jufang He, Junfeng Su, Lau, C, An, ZQ, Su, JF, Feng, YQ, Ed X Wu, Manno, FAM, Yanqiu Feng, Condon Lau, Wu, EX   +15 more
core   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

Lipase inhibition attenuates the acute inhibitory effects of oral fat on food intake in healthy subjects

, 2003
The lipase inhibitor, orlistat, is used in the treatment of obesity and reduces fat absorption by about 30%. However, the mean weight loss induced by orlistat is less than expected for the degree of fat malabsorption.
O'Donovan, D., Wishart, J., Horowitz, M., Feinle-Bisset, C.   +3 more
core   +1 more source

Molecular characterization of CCKR in Ctenopharyngodon idella and its involvement in the intestinal immune response to bacterial challenges

Journal of the World Aquaculture Society
Cholecystokinin receptor (CCKR), an important recognition receptor for the gastrointestinal hormone cholecystokinin (CCK) in the endocrine system, plays a crucial role in regulating immune responses in mammals.
Ran Peng, Jingjing Yang, Huilan Mo, Miao Zhang, Xin Li, Xia Zhang, Meixing Guo, Kelan Jin, Fufa Qu, Jianzhong Li, Yunyun Zeng, Xixun Zhou, Zhuangwen Mao, Zhen Liu, Jianzhou Tang   +14 more
doaj   +1 more source

CKR-1 orchestrates two motor states from a single motoneuron in C. elegans

iScience
Summary: Neuromodulation is pivotal in modifying neuronal properties and motor states. CKR-1, a homolog of the cholecystokinin receptor, modulates robust escape steering and undulation body bending in C. elegans.
Lili Chen, Pan Su, Ya Wang, Yuting Liu, Li-Ming Chen, Shangbang Gao   +5 more
doaj   +1 more source