Results 101 to 110 of about 55,630 (278)
Biomarkers to predict outcomes in diabetic foot ulcers
VIEW, EarlyView.Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro +6 more
wiley +1 more source
Comportamento de coçar e nocicepção evidenciados após a aplicação facial de endotelina-1: um novo teste, uma nova oportunidade farmacológica [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011O presente trabalho reproduziu o modelo experimental descrito por Shimada e Lamotte, (2008), e o
Gomes, Lenyta Oliveira
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BiologySpontaneously hypertensive rats (SHRs) develop severe hypertension and subsequently left ventricular hypertrophy. Whether they also develop right ventricular hypertrophy is not clear. We analyzed 76 female SHRs (strain SHR/NHsd) and observed severe right
Alicia Langer +2 more
doaj +1 more source
Broadening the View: Substance P and Its Metabolism in Pruritus‐Related Diseases
The Journal of Dermatology, EarlyView.ABSTRACT Chronic pruritus is a debilitating symptom accompanying numerous inflammatory skin diseases and remains a major therapeutic challenge. Neurogenic inflammation plays a central role in its pathogenesis, with the tachykinin substance P acting as a key mediator at the interface of the nervous system, immune cells, and cutaneous tissues.
Thomas Walter, Bjoern B. Burckhardt
wiley +1 more source
Cardiovascular Plasticity and Adaptation of High‐Altitude Birds and Mammals
Integrative Zoology, EarlyView.This schematic depicts the cardiovascular adaptations of mammals and birds to high‐altitude hypoxia. It highlights key phenotypic changes in oxygen transport and cardiac responses, driven by molecular mechanisms including transcriptional regulation and genetic modifications.
Huishang She, Yanhua Qu
wiley +1 more source
Allergy, EarlyView.ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj +4 more
wiley +1 more source
Efeitos da endotelina-1 nos ductos biliares extra-hepático e no esfíncter de Oddi isolados de cobaia [PDF]
, 2000 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências BiológicasEste estudo procurou avaliar os efeitos da [endotelina-1] (ET-1) na motilidade de diferentes porções do trato biliar extra-hepático isolado de cobaia.
Koepp, Janice
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New perspectives on VEGF signalling in Alzheimer's disease
Brain Pathology, EarlyView.Emery et al. bring together findings from recent multi‐omic studies, including single‐cell mRNA analysis of human post‐mortem brain tissue, and proteomic analysis of matched CSF and blood samples in large clinical studies. The authors present evidence of the involvement of altered VEGF signalling in vascular and immune dysfunction and neurodegeneration
Cherelle E. G. Emery +2 more
wiley +1 more source
Participação dos prostanóides e do cálcio na contratilidade da vesícula biliar às endotelinas [PDF]
, 2001 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.O estudo avalia as ações contráteis das [endotelinas] (ETs) na [vesícula biliar] (VB) de [cobaia], comparando-as com ...
Maia, Alcíbia Helena de Azevedo
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British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source