Results 161 to 170 of about 55,630 (278)

The Impact of Collection Protocol on the Yield and Purity of Mesenchymal Stem Cell‐Derived Extracellular Vesicles Isolated From Serum‐Free Media

Biotechnology Journal, Volume 21, Issue 7, July 2026.
Graphical Abstract and Lay Summary Mesenchymal stem cells (MSCs) were cultured in standard, ultracentrifuged (UC), or starvation serum‐free media to evaluate how medium influences extracellular vesicle (EV) yield and purity. Culture in UC medium improved EV purity but reduced yield.
Jolene Phelps, Sara Hassanpour Tamrin, Neil A. Duncan, Arindom Sen   +3 more
wiley   +1 more source

Role of endothelin in hypertension

, 1994
Kohler, S. M., Riegger, G. A., Krämer, Bernhard K., Ackermann, M.   +3 more
core   +1 more source

Endothelin-1 and Vasomotor Tone Following Cardioplegic Ischemia/Reperfusion and Cardiopulmonary Bypass. [PDF]

Cells
Kant S, Sellke F, Feng J.
europepmc   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

Comparing bridging drug therapy approaches prior to balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension: a prospective analysis from the national UK CURATE registry. [PDF]

Open Heart
Li OM, Ghani H, Appenzeller P, Amaral-Almeida L, Bambrough P, Cannon JE, Taboada D, Bunclark KL, Toshner M, Sheares K, Coghlan JG, Pepke-Zaba J, Hoole SP.   +12 more
europepmc   +1 more source

Advances in the Neurotoxic Mechanisms of Acrylamide and Multitarget Intervention Strategies of Natural Products

Food Frontiers, Volume 7, Issue 4, July 2026.
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du, Yifan Zhao, Li Dong, Chen Ma, Xiaosong Hu, Daotong Li, Fang Chen, Yinghua Luo   +7 more
wiley   +1 more source

Investigating endothelin receptor B signalling during myelination

, 2017
A key process enabling the correct functioning of neural circuits involves the formation of multi‐layered membranous myelin sheaths around axons. Myelin sheaths, made by specialised glial cells called oligodendrocytes in the central nervous system ...
Swire, Matthew
core  

Abnormalities of liver sinusoidal endothelial cells in primary biliary cholangitis. [PDF]

World J Exp Med
Thalassinos E, Notas G, Xidakis C, Drygiannakis I, Sfakianaki O, Tsomidis I, Kouroumalis E.   +6 more
europepmc   +1 more source

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source

Activin A-Endothelin-1 Axis Governs Pulmonary Vascular Remodeling: Mechanistic Basis for Emerging Therapies in PAH. [PDF]

Arterioscler Thromb Vasc Biol
Faizah NN, Ryanto GRT, Kencana SMS, Suzuki Y, Hara T, Otake H, Emoto N.   +6 more
europepmc   +1 more source