Results 261 to 270 of about 93,761 (300)

Histochemical Studies on Endothelin and the Endothelin-A Receptor in the Hypothalamus

Journal of Cardiovascular Pharmacology, 1998
By use of a rabbit polyclonal antibody specific to the endothelin-A (ETA) receptor, we analyzed the distribution of neurons containing ETA receptors in rat brain. Almost all A1-A7 noradrenergic neurons, A8-A16 and retinal amacrine (A17) dopaminergic neurons (except the A15 group), and C3 adrenergic neurons contained ETA receptors.
H, Yamada, K, Kurokawa
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Endothelin at Pathophysiological Concentrations Mediates Coronary Vasoconstriction via the Endothelin-A Receptor

Circulation, 1995
Background Endothelin-1 (ET-1) is an endothelium-derived vasoconstrictor peptide. Controversy persists regarding the predominant ET receptor that mediates coronary vasoconstriction at pathophysiological concentrations. The aim of the present study was to test the hypothesis that ET mediates local coronary vasoconstriction via ...
C R, Cannan, J C, Burnett, R R, Brandt, A, Lerman   +3 more
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Plasma- and Cerebrospinal Fluid-Immunoreactive Endothelin-1: Effects of Nonpeptide Endothelin Receptor Antagonists with Diverse Affinity Profiles for Endothelin-A and Endothelin-B Receptors

Journal of Cardiovascular Pharmacology, 1998
Some endothelin (ET) receptor antagonists have been reported to elevate plasma immunoreactive endothelin-1 (irET-1). However, there is no information regarding the effects of ET receptor antagonists on cerebrospinal fluid (CSF) levels. To better understand the regulation of circulating and CSF ET-1, the effects of several nonpeptide antagonists with ...
R N, Willette, C F, Sauermelch, B L, Storer, S, Guiney, J I, Luengo, J N, Xiang, J D, Elliott, E H, Ohlstein   +7 more
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Isolation of Endothelin A Receptor from Bovine Lungs

Journal of Cardiovascular Pharmacology, 1995
We isolated endothelin receptor A (ETA) from bovine lungs in a single-step purification procedure using antibodies raised against synthetic peptides that correspond to extra- and intracellular domains of the rat bradykinin receptor. Two receptor species of 55 and 35 kDa were isolated and subjected to N-terminal microsequencing.
S, Hick, J, Godovac-Zimmermann
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Endothelin receptor A expression in human inflammatory cells

Regulatory Peptides, 2009
Most inflammatory diseases show elevated levels of endothelin-1 (ET-1) probably due to an alteration in vascular structure and function with activation/accumulation of inflammatory cells. The ET receptors (ET(A), ET(B)) are widely expressed in all human vessels, consistent with the main role of ET-1 in maintaining physiological vascular tone.
Mencarelli M, Pecorelli A, Carbotti P, VALACCHI, Giuseppe, Grasso G, Muscettola M.   +5 more
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Endothelin-A Receptor in Rat Skeletal Muscle Microvasculature

Microvascular Research, 2002
Although the effect of endothelin-1 (ET-1) on vascular tone has been studied extensively at the arterial/arteriolar level, little is known about the direct effect of ET-1 at the level of the capillary. Using intravital microscopy, we determined capillary red blood cell velocity and arteriolar diameter responses to ET-1, ET(A)-receptor blocker BQ-123 ...
Debra, Mitchell, Aurelia, Bihari, Martin, Sandig, Karel, Tyml   +3 more
openaire   +2 more sources

Endothelin type A receptor

AfCS-Nature Molecule Pages, 2010
Randa Hilal-Dandan, Laurence Brunton
openaire   +1 more source

ET-A Endothelin Receptor

2007
Janet J. Maguire, Anthony Davenport
openaire   +1 more source

Evolution of the endothelin pathway drove neural crest cell diversification

Nature, 2020
Tyler A Square, David Jandzik, Marek Romasek   +2 more
exaly  

Endothelin A Receptor (ETAR)

2012
Randa Hilal-Dandan, Laurence L. Brunton
openaire   +1 more source