Results 71 to 80 of about 44,776 (142)
Recent advances in hypertension and cardiovascular toxicities with vascular endothelial growth factor inhibition [PDF]
, 2017 No abstract ...
Danser, A.H. Jan +4 more
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The Scientific World Journal, 2012 Fluorescence correlation spectroscopy and the newly synthesized Alexa532-ET1 were used to study the dynamics of the endothelin ETA receptor-ligand complex alone and under the influence of a semisynthetic selective antagonist and a fungal extract on ...
Catherina Caballero-George +7 more
doaj +1 more source
Specific Involvement of G Proteins in Regulation of Serum Response Factor-mediated Gene Transcription by Different Receptors [PDF]
, 1998 Regulation of serum response factor (SRF)-mediated gene transcription by G protein subunits and G protein-coupled receptors was investigated in transfected NIH3T3 cells and in a cell line that was derived from mice lacking G_(αq) and G_(α11).
Mao, Junhao +4 more
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Novel pathways of heart failure with preserved ejection fraction [PDF]
, 2016 INTRODUCTION: Diastolic heart failure (HF) i.e., HF with preserved ejection fraction (HFpEF) accounts for ~50% of all clinical HF presentations; but unlike systolic HF i.e., HF with reduced ejection fraction (HFrEF), there are no evidenced based ...
Li, Shanpeng
core +2 more sources
Vascular Health and Risk Management, 2009 Nikolaos Östlund Papadogeorgos, Mattias Bengtsson, Majid KalaniKarolinska Institute, Department of Clinical Sciences, Department of Cardiology, Danderyd Hospital, Stockholm, SwedenBackground: Endothelin-1 may be involved in the development of ...
Nikolaos Östlund Papadogeorgos +2 more
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Acute Pressor Response to Psychosocial Stress Is Dependent on Endothelium‐Derived Endothelin‐1
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 BackgroundAcute psychosocial stress provokes increases in circulating endothelin‐1 (ET‐1) levels in humans and animal models. However, key questions about the physiological function and cellular source of stress‐induced ET‐1 remain unanswered.
Brandon M. Fox +9 more
doaj +1 more source
Cellular and molecular mediators of bone metastatic lesions [PDF]
, 2018 Bone is the preferential site of metastasis for breast and prostate tumor. Cancer cells establish a tight relationship with the host tissue, secreting factors that stimulate or inhibit bone cells, receiving signals generated from the bone remodeling ...
Battafarano, Giulia +3 more
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A review of sitaxsentan sodium in patients with pulmonary arterial hypertension
Vascular Health and Risk Management, 2007 Aaron B WaxmanDepartment of Internal Medicine, Pulmonary Critical Care Unit, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USAAbstract: Pulmonary arterial hypertension (PAH) is a life threatening, progressive condition which ...
Aaron B Waxman
doaj
Strategies for anti-fibrotic therapies. [PDF]
, 2013 The fibrotic diseases encompass a wide spectrum of entities including such multisystemic diseases as systemic sclerosis, nephrogenic systemic fibrosis and sclerodermatous graft versus host disease, as well as organ-specific disorders such as pulmonary ...
Jimenez, Sergio A. +2 more
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Artery Research, 2009 Background. Experimental cerebral ischemia and organ culture of cerebral arteries result in enhanced expression of endothelin ETB receptors in smooth muscle cells. The present study was designed to evaluate the involvement of calcium-calmodulin dependent
R. Waldsee +3 more
doaj +1 more source