Results 71 to 80 of about 55,630 (278)

Participação das endotelinas e seus receptores na neuralgia do trigêmeo: mecanismos operados em células do gânglio trigeminal [PDF]

open access: yes, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2015.Este estudo avaliou a habilidade da endotelina-1 (ET-1) em promover hiperalgesia orofacial ao calor ...
Gomes, Lenyta Oliveira
core  

Endothelins. Myocardial actions of a new class of cytokines [PDF]

open access: yes, 1992
There is growing evidence to support the existence of a dynamic interaction in vivo between cardiac myocytes and adjacent microvascular endothelial cells in the regulation of both cardiac myocyte and possibly endothelial cell phenotype and function ...
Smith, T. W.   +3 more
core   +1 more source

The Involvement of Endothelin Pathway in Chronic Psychological Stress-Induced Bladder Hyperalgesia Through Capsaicin-Sensitive C-Fiber Afferents

open access: yesJournal of Inflammation Research, 2022
Chuying Qin,1 Yinhuai Wang,1 Sai Li,2 Yuanyuan Tang,3 Yunliang Gao1 1Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, 410011, People’s Republic of China; 2Acupuncture and Tuina School, Hunan University of Chinese ...
Qin C, Wang Y, Li S, Tang Y, Gao Y
doaj  

Endothelin signalling mediates experience-dependent myelination in the CNS

open access: yeseLife, 2019
Experience and changes in neuronal activity can alter CNS myelination, but the signalling pathways responsible remain poorly understood. Here we define a pathway in which endothelin, signalling through the G protein-coupled receptor endothelin receptor B
Matthew Swire   +4 more
doaj   +1 more source

Predictive Biomarkers in Metastatic Colorectal Cancer Patients Treated With Bevacizumab: A Turkish Oncology Group (TOG) Study

open access: yesInternational Journal of Cancer, EarlyView.
Bevacizumab added to systemic chemotherapy remains a cornerstone of metastatic colorectal cancer treatment, but its effectiveness is variable. Tumors can bypass the VEGF blockade by activating other pro‐angiogenic pathways, hampering the identification of predictive biomarkers.
Büsra Akay Hacan   +9 more
wiley   +1 more source

Maternal and perinatal outcomes of pregnant women with echocardiographically high probability of pulmonary arterial hypertension

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aimed to describe maternal and perinatal outcomes among pregnant women with echocardiographically high probability of pulmonary arterial hypertension (PAH) managed at a quaternary center and to compare outcomes between women with and without cardiac complications (CC).
Laura Belmont‐Rojo   +6 more
wiley   +1 more source

Distribution of Endothelin Receptor Subtypes in the Rat Kidney Renal and Haemodynamic Effects of the Mixed (A/B) Endothelin Receptor Antagonist Bosentan [PDF]

open access: yes, 1995
Summary: The paracrine renal endothelin system has been implicated in acute and chronic kidney diseases. How-ever, there are only few data about the expression of endothelin receptor subtypes and their impact on renal function in the normal rat kidney ...
Volker Yogi   +20 more
core   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

Endothelin‐1 and Endothelin Receptor Antagonists in Cardiovascular Remodeling

open access: yesProceedings of the Society for Experimental Biology and Medicine, 1999
Endothelins build a peptide family composed of three isoforms, each of them containing 21 amino acids. Endothelin‐1 is the isoform mainly responsible for any cardiovascular action and therefore the sole scope of this review. Endothelin‐1 is the most potent endogenous vasoconstrictor known; in addition it acts as a potent (co)mitogen.
M, Kirchengast, K, Münter
openaire   +2 more sources

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