Results 211 to 220 of about 66,098 (241)
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Expression of the c-erbB-2-encoded oncoprotein and progesterone receptor in human meningiomas
Acta Neuropathologica, 1993The present study investigated the expression of c-erbB-2 in 59 meningiomas, including different histological subtypes and anaplastic variants, by immunocytochemistry and molecular biological techniques. Immunohistochemistry using the monoclonal antibody FWP-51 directed against c-erbB-2-encoded oncoprotein gp185 demonstrated variable degrees of ...
J, Schlegel +6 more
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c-erbB-2 Oncoprotein and Epidermal Growth Factor Receptor in Cervical Lesions
Pathobiology, 1997Epidermal growth factor receptor (EGF-R) and the oncogene product of c-erbB-2 have been shown to be expressed in human tumors and in some cases relate to clinical outcome. This study investigates the correlation between the presence of these receptor proteins and various histological grades of cervical tissues.
S, Lakshmi +5 more
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Journal of Urology, 1996
To study the c-erbB-2 oncogene in primary transitional cell bladder cancer.Ninety-five patients with known clinical follow-up and epidermal growth factor receptor (EGFr) status were studied for expression of c-erbB-2 by immunostaining. Possible mechanisms underlying increased staining for c-erbB-2 protein were investigated by analyzing DNA and RNA ...
J K, Mellon +5 more
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To study the c-erbB-2 oncogene in primary transitional cell bladder cancer.Ninety-five patients with known clinical follow-up and epidermal growth factor receptor (EGFr) status were studied for expression of c-erbB-2 by immunostaining. Possible mechanisms underlying increased staining for c-erbB-2 protein were investigated by analyzing DNA and RNA ...
J K, Mellon +5 more
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Expression of the c-erbB-2 gene encoding a growth factor receptor.
Princess Takamatsu symposia, 1988The c-erbB-2 gene is a v-erbB-related proto-oncogene which encodes a protein similar to but distinct from the epidermal growth factor (EGF) receptor. In situ hybridization of metaphase spread showed that this gene is located on human chromosome 17 at q21, a specific breakpoint observed in a translocation associated with acute promyelocytic leukemia ...
T, Yamamoto +4 more
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Pathology - Research and Practice, 2008
The aims of this study were twofold: (i) to determine the occurrence frequency of apocrine carcinoma of the breast (ApBCa) in Turkish breast cancer (BCa) patients; and (ii) to evaluate the expression of estrogen receptor (ER), progesterone receptor (PR), androgen receptor (AR), gross cystic disease protein-15 (GCDFP-15), c-erbB-2, and p53 in these ...
Handan, Kaya +3 more
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The aims of this study were twofold: (i) to determine the occurrence frequency of apocrine carcinoma of the breast (ApBCa) in Turkish breast cancer (BCa) patients; and (ii) to evaluate the expression of estrogen receptor (ER), progesterone receptor (PR), androgen receptor (AR), gross cystic disease protein-15 (GCDFP-15), c-erbB-2, and p53 in these ...
Handan, Kaya +3 more
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Biochemistry and cell biology = Biochimie et biologie cellulaire, 1997
The erbB family of tyrosine kinase receptors is involved in the regulation of a variety of vital functions including cell proliferation, cell differentiation, and stress response. Alteration in the expression of erbB receptors occurs in numerous tumor types and plays an important role in cancer development, cancer progression, and susceptibility to ...
Alaoui-Jamali, M. A. +3 more
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The erbB family of tyrosine kinase receptors is involved in the regulation of a variety of vital functions including cell proliferation, cell differentiation, and stress response. Alteration in the expression of erbB receptors occurs in numerous tumor types and plays an important role in cancer development, cancer progression, and susceptibility to ...
Alaoui-Jamali, M. A. +3 more
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Oncogene, 1993
The endocytosis of gp185erbB-2 was studied using chimeric receptors in which the intracellular domain of erbB-2, or subdomins thereof, was substituted for the corresponding regions of the epidermal growth factor (EGF) receptor. Chimeric and wild-type EGF or erbB-2 receptors were expressed in mouse NIH3T3 or NR6 fibroblasts and in a human mammary ...
A. Sorkin, P. P. Di Fiore, G. Carpenter
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The endocytosis of gp185erbB-2 was studied using chimeric receptors in which the intracellular domain of erbB-2, or subdomins thereof, was substituted for the corresponding regions of the epidermal growth factor (EGF) receptor. Chimeric and wild-type EGF or erbB-2 receptors were expressed in mouse NIH3T3 or NR6 fibroblasts and in a human mammary ...
A. Sorkin, P. P. Di Fiore, G. Carpenter
openaire +2 more sources
P53, c-erbB-2 expression and steroid hormone receptors in breast carcinoma
2004Objective: The aim of the study was to evaluate the p53 tumor suppressor gene, c-erbB-2 and steroid hormone receptor expression in breast carcinoma by immunohistochemistry and to correlate them with different histopathologic parameters. Materials and Methods: p53, c-erbB-2, steroid hormone receptors and their correlation with age, tumor size ...
Kilinç, N, Yaldiz, M
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Recombinant single chain immunotoxins specific for the EGF receptor and ErbB-2
European Journal of Cancer, 1995Mathias Schmidt +3 more
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The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease
Cancer Cell, 2019Bettina Wingelhofer +2 more
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