Results 111 to 120 of about 71,317 (233)

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

Molecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez, Antonio Vico‐Padilla, Claus Schneider, Juan Carlos Espín, Antonio González‐Sarrías, Juan Antonio Giménez‐Bastida   +5 more
wiley   +1 more source

Tomato Puree Enrichment in a High‐Fat Meal Reduces Postprandial Plasma and Adipose Tissue Inflammation Biomarkers in Healthy Male Adults: A Crossover Randomized Controlled Trial

Molecular Nutrition &Food Research, EarlyView.
Tomato puree enrichment in the context of a high‐fat meal in healthy adult males leads to a significant reduction of systemic postprandial and adipose tissue postprandial inflammation. ABSTRACT The postprandial period is marked by increased plasma inflammatory biomarkers and heightened adipose tissue inflammation.
Lea Sani, Julien Astier, Djaffar Ould‐Ali, Patrick Borel, Jean‐François Landrier   +4 more
wiley   +1 more source

Lactobacillus rhamnosus PB01 Oral Supplementation Alleviates Metabolic and Reproductive Dysfunctions in Type 1 Diabetic Male Rats

Molecular Nutrition &Food Research, EarlyView.
Type 1 diabetes mellitus is known to impair reproductive function in males of reproductive age. This study investigated the effects of a 7‐week course of oral supplementation with the probiotic Lactobacillus rhamnosus PB01 on metabolic and fertility parameters in diabetic male rats.
Sihan Liu, Hiva Alipour, Malwina Ulanowska, Vladimir Zachar, Fereshteh Dardmeh   +4 more
wiley   +1 more source

Microfluidic Systems in Cancer Diagnosis: Advancing Exosome and CTC Detection From Laboratory Research to Clinical Application

Nano Select, EarlyView.
Detection of cancer through the identification of EV markers and CTCs using microfluidic systems is rapidly advancing. These markers are typically identified from liquid biopsy samples, which offer a highly favorable alternative to traditional biopsy methods due to their non‐invasive nature.
Bahareh Valinezhad Saghezi, Kamran Mansouri, Rahman Hallaj   +2 more
wiley   +1 more source

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

Neuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal, Saurabh Singhal, Bernhard T. Baune   +2 more
wiley   +1 more source

Patterns of Teprotumumab‐Induced Hearing Dysfunction: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Hearing loss has been reported after administration of the monoclonal antibody teprotumumab. The purpose of this study was to review available evidence regarding the patterns of teprotumumab‐related ototoxicity. Data Sources PubMed, EMBASE, and Cochrane Library.
Kevin Wong, Priya Arya, Yansy Salmeron, Douglas C. Bigelow, Michael J. Ruckenstein, Shubhasree Banerjee, Madhura Tamhankar, Jason A. Brant, Tiffany P. Hwa   +8 more
wiley   +1 more source

Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation

Sensory Neuroscience, EarlyView.
ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera, Nicole Ramones, Isabella Moceri, Sanjoy K. Bhattacharya   +3 more
wiley   +1 more source

Fabricating Microfluidic Co‐Cultures of Immortalized Cell Lines Uncovers Robust Design Principles for the Simultaneous Formation of Patterned, Vascularized, and Stem Cell‐Derived Adipose Tissue

Small, EarlyView.
Murphy et al present an optimized co‐culture protocol for immortalized cell line vasculogenesis. Here, immortalized co‐cultures form reproducible microvessel networks across 31‐days, while gradient microchips enable simultaneous mesenchymal stem cell (MSC) adipogenesis and endothelial cell (EC) vasculogenesis.
Ashley R. Murphy, Rose Ann Franco, Mark C. Allenby   +2 more
wiley   +1 more source

Cord blood levels of insulin‐like growth factor‐1 and insulin‐like growth factor binding protein‐3 correlate with perinatal brain development in fetal congenital heart disease

Ultrasound in Obstetrics &Gynecology, EarlyView.
Abstract Objectives Neonates with critical congenital heart disease (CCHD) are at risk for adverse early brain development and long‐term neurodevelopmental sequelae. Insulin‐like growth factor‐1 (IGF‐1) and insulin‐like growth factor binding protein‐3 (IGFBP‐3) are essential contributors to brain growth and maturation.
M. Nijman, N. H. P. Claessens, J. M. P. J. Breur, L. Reijn, N. J. G. Jansen, I. M. van Ooijen, R. de Heus, C. H. Nijboer, M. N. Bekker, M. J. N. L. Benders, R. Stegeman, J. E. G. Vaes, the CHD LifeSpan Study Group Utrecht, Joppe Nijman, Thomas Alderliesten, Rian Bosch, Roelie M. Wösten‐van Asperen, Henriette ter Heide, Trinette J. Steenhuis, Martijn G. Slieker, Gabrielle G. van Iperen, Kim van Loon, Boyd V. Martherus, Erik Koomen, Abraham van Wijk, Paul H. Schoof, Hanna Talacua, Neeltje Crombag, Bauke M. Adriaanse, Niels Blanken, Rutger A.J. Nievelstein, Monique M.J. van Schooneveld, Lotte Soeters, Maaike C.A. Sprong   +33 more
wiley   +1 more source