Results 161 to 170 of about 3,230,451 (211)
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1989
Many hormones and other extracellular stimuli exert their effects by binding to specific receptors on the plasma membrane of cells. The receptors recognize and bind the agonists with high affinity, and are therefore responsible for initiating the cascade of reactions leading to intracellular events. The hormone-receptor complex transmits this signal in
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Many hormones and other extracellular stimuli exert their effects by binding to specific receptors on the plasma membrane of cells. The receptors recognize and bind the agonists with high affinity, and are therefore responsible for initiating the cascade of reactions leading to intracellular events. The hormone-receptor complex transmits this signal in
openaire +2 more sources
Insulin receptors and the site of action of insulin
Life Sciences, 1978Abstract There is considerable evidence that insulin receptors located on the plasma membrane of target cells directly mediate the short- term effects of insulin on plasma membrane functions such as glucose transport. These receptors are composed of four subunits, contain two or more binding sites, and show features of negative cooperativity. Insulin
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Evolution of Insulin and Insulin Receptors
1987Insulin traditionally has been considered to be a unique product of the vertebrate pancreas. More recent studies, however, have suggested that there may be extrapancreatic sources of insulin and that insulin may act on tissues other than its classic target tissues.
William L. Lowe +2 more
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Insulin receptor‐insulin interaction kinetics using multiplex surface plasmon resonance
Journal of Molecular Recognition, 2013Kannan Subramanian +4 more
semanticscholar +1 more source
Annual Review of Pharmacology and Toxicology, 1983
S, Jacobs, P, Cuatrecasas
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S, Jacobs, P, Cuatrecasas
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Post-receptor insulin resistance after diazoxide in non-insulin dependent diabetes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986S. Olczak, R. Greenwood, C. Hales
semanticscholar +2 more sources