Results 121 to 130 of about 6,575 (222)

Research on the effects and related mechanisms of geomagnetic storm on depression

Brain Research Bulletin
Objective: Depression has become disabling disease in the world. Geomagnetic storm is closely related to depression behavior, and melatonin is an important factor in the pathogenesis of depression. This study observed the effects of different intensities
Hui Wu, Yuan Yang, Weiyu Chang, Xinli Chen, Shiqi Yang, Min Xu, Keyu Liu, Yu Yun, Liang Dong   +8 more
doaj   +1 more source

GPR50 is the mammalian ortholog of Mel1c: Evidence of rapid evolution in mammals

BMC Evolutionary Biology, 2008
Background The melatonin receptor subfamily contains three members Mel1a, Mel1b and Mel1c, found in all vertebrates except for Mel1c which is found only in fish, Xenopus species and the chicken.
Malpaux Benoit, Pontarotti Pierre, Callebaut Isabelle, Migaud Martine, Levasseur Anthony, Dufourny Laurence, Monget Philippe   +6 more
doaj   +1 more source

The Effect of Melatonin on Behavioral, Molecular, and Histopathological Changes in Cuprizone Model of Demyelination [PDF]

, 2016
Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. The protective effects of melatonin (MLT) on various neurodegenerative diseases, including MS, have been suggested.
Ghadiri, T., Ghaemi, A., Gorji, A., Khodagholi, F., Noorbakhsh, F., Sharifzadeh, M., Vakilzadeh, G.   +6 more
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Effect of Melatonin on Chemoresistance Exhibited by Spheres Derived from Canine Mammary Carcinoma Cells

Animals
Mammary cancer is a frequent disease in female dogs, where a high proportion of cases correspond to malignant tumors that may exhibit drug resistance. Within the mammary tumor microenvironment, there is a cell subpopulation called cancer stem cells (CSCs)
Dania Cataldo, Guillermo Aravena, Alejandro Escobar, Julio C. Tapia, Oscar A. Peralta, Cristian G. Torres   +5 more
doaj   +1 more source

Melatonin May Improve Post-Thaw Sperm Motility in Epinephelus fuscoguttatus by Potentially Regulating Mitochondrial mPTP via the MT2/PI3K/GSK-3β Pathway: First Evidence in Teleosts

Antioxidants
Melatonin, a well-known antioxidant, has been widely used in sperm cryopreservation of various animals, but its regulatory mechanism in fish remains unclear.
Yuxin Zhang, Qingxin Ruan, Weiwei Zhang, Yingxin Wu, Jiajie Li, Qinghua Wang, Fanming Guo, Yang Yang, Zining Meng   +8 more
doaj   +1 more source

Association between rs2119882 (MT1A) Melatonin Receptor Polymorphism and Childhood Leukemia Using RFlP-PCR Method

Journal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Melatonin is a well-known neuroendocrine reproductive hormone-based hormone that has an important role in the circadian clock system and has potent antioxidant properties.
Mohaddeseh Nemati, Hossein Karami, Abbasali Dehpouri Jouibari, Abbas Mohammadpour, sekineh Jalalzadeh, Ramin Ataee   +5 more
doaj  

Ожиріння: роль десинхронозу та генетичних чинників у механізмах його розвитку [PDF]

, 2017
Висвітлено роль десинхронозу та генетичних чинників у розвитку ожиріння. Проаналізовано окремі патогенетичні ланки розвитку ожиріння та вплив на них мелатоніну.
Пішак, Василь Павлович, Ризничук, Мар'яна Олександрівна   +1 more
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Melatonin: a promising therapy to combat type 2 airway inflammation via MT1-Sirt1 pathway

Frontiers in Pharmacology
BackgroundsType 2 asthma is characterized by airway inflammation, mucus hypersecretion, and remodeling, and circadian rhythm dysregulation is implicated in its pathogenesis.
Zhe Zhang, Jie Jiang, Guilian Chen, Xiuqin Zhang, Jipeng Wang, Baolan Wang   +5 more
doaj   +1 more source

Light pollution during pregnancy influences the growth of offspring in rats

Ecotoxicology and Environmental Safety
Objective: To investigate the effects of excessive light exposure during gestation on intrauterine development and early growth of neonates in rats. Methods: Pregnant rats were randomly allocated to three groups: the constant light exposure group, non ...
Baojing Zhao, Zhen Yu, Junjie Sun, Weisheng Cheng, Tao Yu, Yuanyuan Yang, Zhaolian Wei, Zongzhi Yin   +7 more
doaj   +1 more source

Estudios básicos y clínicos sobre la melatonina como ejemplo de medicina traslacional [PDF]

, 2015
A esta altura de la vida uno se siente tentado a detenerse y reflexionar sobre lo que la vida profesional le ha deparado. En mi caso se cumplen 50 años de mi relación con la glándula pineal y la melatonina y reconozco la inmensa fortuna de haberme ...
Cardinali, Daniel Pedro
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