Results 131 to 140 of about 12,342 (188)

The neural niche in cancer: mechanistic insights into tumor-neuron-immune crosstalk and therapeutic opportunities. [PDF]

Front Cell Dev Biol
Aysit N, Altintas E, Koksalar Alkan F, Ozturk G, Korkaya H.   +4 more
europepmc   +1 more source

The Central Cholinergic Synapse: A Primer. [PDF]

Int J Mol Sci
Klein J.
europepmc   +1 more source

Bladder Dysfunction in Sickle Cell Disease Is Associated with Inflammation and Oxidative Stress. [PDF]

Int J Mol Sci
Pereira DA, Calmasini FB, Silveira THR, Pereira DA, de Oliveira MG, Costa FF, Silva FH.   +6 more
europepmc   +1 more source

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Regulation of muscarinic M2 receptors

Life Sciences, 1997
The molecular mechanisms involved in the regulation of muscarinic receptor gene expression are poorly understood. In an effort to gain a better understanding of the regulation of M2 receptors, we have investigated homologous and heterologous regulation of M2 muscarinic receptor protein and gene expression in human embryonic lung fibroblasts (HEL 299 ...
P J, Barnes, E B, Haddad, J, Rousell
openaire   +2 more sources

m2-Toxin: A Selective Ligand for M2 Muscarinic Receptors

Molecular Pharmacology, 1999
Selective ligands are needed for distinguishing the functional roles of M2 receptors in tissues containing several muscarinic receptor subtypes. Because the venom of the green mamba Dendroaspis angusticeps contains the most specific antagonists known for M1 and M4 receptors (m1-toxin and m4-toxin), it was screened for toxins that inhibit the binding of
J M, Carsi, H H, Valentine, L T, Potter
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Kinetic and biophysical analysis of the m2 muscarinic receptor

Life Sciences, 1995
The recombinant Pm2 muscarinic receptor expressed in Chinese hamster ovary (CHO) cells was used as a model system to examine receptor-effector coupling and ligand binding. In CHO cells, equilibrium binding studies and the dependence on receptor number per cell of the maximum response and EC50 values for agonist stimulation of phosphatidylinositol ...
B T, Hirschberg, V A, Mosser, G L, Peterson, A, Toumadje, W K, Vogel, W C, Johnson, M I, Schimerlik   +6 more
openaire   +2 more sources

A model of the human M2 muscarinic acetylcholine receptor

Journal of Computer-Aided Molecular Design, 2002
The M2 muscarinic acetylcholine receptor belongs to the family of rhodopsin like G-Protein Coupled Receptors. This subtype of muscarinic receptors is of special interest because it bears, aside from an orthosteric binding site, also an allosteric binding site.
Kirstin Jöhren, Hans-Dieter Höltje
openaire   +2 more sources