Results 131 to 140 of about 13,945 (210)

The dual-site agonist for human M2 muscarinic receptors Iper-8-naphtalimide induces mitochondrial dysfunction in <i>Saccharomyces cerevisiae</i>. [PDF]

Microb Cell
Cirigliano A, Amelina A, Passarini E, Ricelli A, Balasco N, Mori M, Botta B, De Stefano ME, Papotto C, Guerriero C, Tata AM, Rinaldi T.   +11 more
europepmc   +1 more source

mPFC Synaptosome Proteomics Reveals Novel Pathways and Muscarinic Receptor Changes in a Learned Helplessness Mouse Model. [PDF]

eNeuro
Abdulla ZI, Garcia-Milian R, Giahyue E, Fertuzinhos S, Collin F, Wang W, Lam TT, Nairn AC, Picciotto MR.   +8 more
europepmc   +1 more source

Evaluation of an Agonist Index: Affinity Ratio for Compounds Active on Muscarinic Cholinergic M2 Receptors

, 1999
A protocol for predicting full agonist, partial agonist, and antagonist profiles of compounds with M2 muscarinic cholinergic receptor activity was developed using radioligand binding assay techniques with [3H]-N-methyl scopolamine (NMS) and [3H ...
AMENTA, Francesco, PIERGENTILI, Alessandro, TAYEBATI, Seyed Khosrow, NATALE D.   +3 more
core  

Autonomic Receptor Autoantibodies in Complex Regional Pain Syndrome and Other Chronic Pain Conditions: A Cross-Sectional Analysis. [PDF]

Biomedicines
van der Spek DPC, Hoffenkamp RH, Huygen FJPM, Bharwani KD, Eijkelkamp N, Dirckx M.   +5 more
europepmc   +1 more source

The Dependence of M2 Muscarinic Receptor Signaling on the Formation of a Disulfide Bridge

, 2015
Muscarinic receptors are G-protein coupled acetylcholine receptors made up of seven transmembrane loops. On the M2 receptor, the second and the third extracellular domain are linked by two cysteine residues forming an intramolecular disulfide bridge ...
Frye, Hannah
core  

Long-Acting Muscarinic Antagonists for the Treatment of Difficult-to-Treat and Severe Asthma: A Narrative Review Focusing on Inflammation from Bench to Bedside. [PDF]

J Inflamm Res
Calzetta L, Manzetti GM, Pistocchini E, Lauro RF, Gholamalishahi S, Cazzola M, Rogliani P.   +6 more
europepmc   +1 more source

Autoantibodies against M2 muscarinic receptors in patients with cardiomyopathy display non-desensitized agonist-like effects

, 1999
Circulating autoantibodies against the human M2 muscarinic receptors have been previously shown in 38% of patients with idiopathic dilated cardiomyopathy. The functional properties of these autoantibodies are reported herein.
Matsui, S, Hjalmarson, Åke,, Fu, H M, Wallukat, G, Fu, Michael,   +4 more
core  

Dopamine and Acetylcholine in the Striatum: Circuit Interactions and Behavioral Control in Substance Use Disorders. [PDF]

Brain Sci
Dinckol O, Wenger NH, Copling A, Patel BP, Kutlu MG.   +4 more
europepmc   +1 more source

Exploring the Evolving Role of Scopolamine in Pharmacotherapy: From Cognitive Impairment to Neuroplasticity?-A Narrative Review. [PDF]

Molecules
Kukla J, Olejnik P, Kasarełło K.
europepmc   +1 more source

Negative Allosteric Modulation of Agonist-Induced M₂ Muscarinic Receptor/β-Arrestin Interaction by Serum Autoantibodies from Patients with Chronic Chagas Disease. [PDF]

Cells
Carrera Páez LC, Beltrame SP, Auger SR, Sabra AH, Bilder CR, Irurzun IM, Waldner CI, Goin JC.   +7 more
europepmc   +1 more source