Results 121 to 130 of about 13,945 (210)

Allosteric interactions at the m1, m2 and m3 muscarinic receptor subtypes

, 1991
The purpose of our study was to investigate the interactions of allosteric antagonists at the individual m1, m2 and m3 muscarinic receptor subtypes. This was achieved through the use of transformed Chinese hamster ovary cells stably expressing the rat m1
Lee, N. H., El-Fakahany, E. E.
core  

Modifying Muscarinic Signaling through Mutation of the Neurotransmitter Receptor M2\u27s G-Protein

, 2013
Muscarinic receptors are a class of G-protein-coupled receptors which recognize Acetylcholine to activate three main signaling systems. The path that the signal follows is determined by the G-protein with which the receptor communicates.
Frye, Hannah
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Active immunization of combined beta1-adrenoceptor and M2-muscarinic receptor peptides induces cardiac hypertrophy in rabbits

, 1999
BACKGROUND: The high prevalence of patients with dilated cardiomyopathy (DCM) with anti-beta1-adrenoceptor and/or anti-M2-muscarinic receptor autoantibodies in their sera has been observed.
Matsui, S, Kurihara, T, Teraoka, K, Yamaguchi, N, Hayase, M, Fu, Michael,, Takekoshi, N, Katsuda, S   +7 more
core  

Molecular dynamics simulations of the muscarinic receptor [PDF]

, 2015
Title: Molecular dynamics simulations of the muscarinic receptor Author: Radim Cajzl Department: Institute of Physics of Charles University Supervisor: RNDr.
Cajzl, Radim
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Modulation of M1 and M2 muscarinic receptor subtypes following repeated organophosphate exposure in rats

, 1992
Repeated exposure to organophosphates has been shown to cause a decrease in muscarinic cholinergic receptors in the central and peripheral nervous system.
Costa, L. G., Fitzgerald, B. B
core  

A complex interplay of various intracellular motifs determines G protein binding and activation of muscarinic receptors. [PDF]

Sci Rep
Kirchhofer SB, Jelinek V, Klingelhöfer K, Krett AL, Bünemann M.   +4 more
europepmc   +1 more source

Receptor architecture of the macaque lateral geniculate nucleus. [PDF]

Brain Struct Funct
Saito M, Rapan L, Niu M, Zhao L, Tsujimura SI, Takemura H, Palomero-Gallagher N.   +6 more
europepmc   +1 more source

Dualsteric Agonist for M2 Muscarinic Receptor Causes Oxidative Stress and Mitochondrial Alteration in Human Glioblastoma Cancer Stem Cells. [PDF]

J Neurochem
Guerriero C, De Nuccio C, Petrone M, Rinaldi T, Cirigliano A, Visentin S, Bernardo A, Conti L, Matera C, De Amici M, Dallanoce C, Tata AM.   +11 more
europepmc   +1 more source

Simultaneous release of glutamate and acetylcholine from single magnocellular "cholinergic" basal forebrain neurons

, 2006
Basal forebrain (BF) neurons provide the principal cholinergic drive to the hippocampus and cortex. Their degeneration is associated with the cognitive defects of Alzheimer's disease. Immunohistochemical studies suggest that some of these neurons contain
Allen, TGJ, Abogadie, FC, Brown, DA
core  

Acetylcholine in Brain-Body Communication: Biological Mechanisms and Physiological Roles. [PDF]

Int J Mol Sci
Gao Y, Zhou T, Lai X, Fei E.
europepmc   +1 more source