Results 61 to 70 of about 13,945 (210)

Gastroenterological Society of Australia Position Statement on the Assessment and Management of Idiopathic Gastroparesis

Journal of Gastroenterology and Hepatology, EarlyView.
The first Australian guidance document on the assessment and management of idiopathic gastroparesis (IGP) reconceptualises IGP as a sensorimotor disorder. It proposes a novel multidisciplinary treatment algorithm and 20 high‐consensus recommendations, addressing common overlapping disorders, and providing clear guidance on associated disordered eating ...
Trina Kellar, Chamara Basnayake, Jessica Biesiekierski, Rebecca Burgell, Jessica Fitzpatrick, Geoffrey Hebbard, Vincent Ho, Hannah Kim, Simon R. Knowles, Christopher K. Rayner, May Wong, Nicholas J. Talley   +11 more
wiley   +1 more source

Impact of TCAs and Gabapentin on Saliva and BMI in Adults With Xerostomia

Journal of Oral Rehabilitation, EarlyView.
In adults with medication‐related xerostomia, tricyclic antidepressant and gabapentin use were not independently associated with BMI or oral dryness after adjustment. Instead, female sex, anticholinergic burden, obstructive sleep apnea, GERD, thyroid disease, depression and race demonstrated stronger associations with reduced salivary flow and greater ...
Waldir Martineli Filho, Andre Pedroso, Alhanoof Khaled Alarfaj, Karina Dutra Pinto Pereira, Abdul Basir Barmak, Szilvia Arany   +5 more
wiley   +1 more source

Adreno-Muscarinic Synergy of Contractile Responses From Human Hyperplastic Prostate [PDF]

International Neurourology Journal
Purpose Adreno-muscarinic synergy, a supra-additional contractile response to simultaneous application of α-adrenoreceptor and muscarinic receptor agonists, is a feature of several lower urinary tract regions that have dual sympathetic and ...
Ben T. Blake-James, Basu Chakrabarty, Christopher H. Fry   +2 more
doaj   +1 more source

Test–retest reliability of Doppler ultrasound‐based leg blood flow assessments during exercise in patients with chronic obstructive pulmonary disease

Experimental Physiology, Volume 111, Issue 6, Page 2987-2999, 1 June 2026.
Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad, Jacob P. Hartmann, Amalie B. Andersen, Helene L. Hartmeyer, Ulrik W. Iepsen, Ronan M. G. Berg   +5 more
wiley   +1 more source

Acetylcholine muscarinic M2 receptor maintains human Schwann-like adipose-derived phenotype in the absence of differentiating medium

Cell Death Discovery
Human adipose-derived stem cells (ASCs), differentiated in vitro towards Schwann-like phenotype (hdASCs), have been suggested as an alternative source of Schwann cells (SCs).
Roberta Piovesana, Alessandro Faroni, Ada Maria Tata, Adam J. Reid   +3 more
doaj   +1 more source

Antagonist binding profile of the split chimeric muscarinic m2-trunc/m3-tail receptor

, 1998
Recent evidence suggests that G-protein-coupled receptors can behave as multiple subunit receptors, and can be split into parts, maintaining their binding ability.
MINARINI A, Barbier P., BARBIER P, Tumiatti V., Corsini G. U., BOLOGNESI ML, MAGGIO R., Colelli A., MELCHIORRE C, COLELLI A, Minarini A., CORSINI, GIOVANNI UMBERTO, Bolognesi M. L., TUMIATTI V, Melchiorre C.   +14 more
core   +1 more source

Effects of Transcutaneous Electrical Nerve Stimulation, Electrical Muscle Stimulation, Exercise and Heat on Back Pain—A Randomized Controlled Clinical Exploratory Trial

European Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background This randomized controlled study compared different forms of therapy for chronic back pain. Methods Seventy‐nine patients with chronic back pain with a duration of symptoms of more than 6 months were included in the study and randomly assigned to one of four therapy groups (a) sports therapy with a focus on strength training (SG ...
Thorsten Schmidt, Sonja Kossiski, Hanna Kornprobst, Laura von Levern, Dominik M. Schulte, Manon Sendel, Ralf Baron, Janne Gierthmühlen   +7 more
wiley   +1 more source

Role of K+ Channels in M2 Muscarinic Receptor-Mediated Inhibition of Noradrenaline Release From the Rat Stomach

Journal of Pharmacological Sciences, 2004
Previously we reported the cholinergic M2 muscarinic receptor-mediated inhibition of noradrenaline release from the rat stomach (K. Yokotani, Y. Osumi. J Pharmacol Exp Ther. 1993;264:54–60).
Kumiko Nakamura, Shoshiro Okada, Naoko Yamaguchi, Takahiro Shimizu, Keiko Yokotani, Kunihiko Yokotani   +5 more
doaj   +1 more source

Modulation of M2 muscarinic receptor–receptor interaction by immunoglobulin G antibodies from Chagas' disease patients

, 2011
Summary Circulating immunoglobulin (Ig)G antibodies against M2 muscarinic acetylcholine receptors (M2 mAChR) have been implicated in Chagas' disease (ChD) pathophysiology.
C I Waldner, J C Goin, S P Beltrame, S R Auger, C R Bilder   +4 more
core   +1 more source

Prehospital Use of Non‐Invasive Ventilation for Acute Respiratory Failure due to Acute Exacerbation of Chronic Obstructive Pulmonary Disease. A Randomised Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background In‐hospital use of non‐invasive ventilation improves outcomes in patients with acute respiratory failure caused by acute exacerbation of chronic obstructive pulmonary disease. Prehospital use of non‐invasive ventilation is uncommon due to diagnostic uncertainty and logistical constraints.
Jesper H. Brendel, Lars W. Andersen, Søren H. Skaarup, Thomas Dissing, Anders Gunnar Nielsen, Nikolaj F. Milandt, Ulrick S. Espelund, Lisa F. Irion, Lone R. Mortensen, Kim M. Larsen, Jens Aage K. Petersen   +10 more
wiley   +1 more source