Results 211 to 220 of about 83,203 (255)

Role of Notch gene receptors as prognostic biomarkers in colorectal cancer. [PDF]

open access: yesSci Rep
Sharma AK   +8 more
europepmc   +1 more source

Methylation Landscapes of Cartilage in Hip Osteoarthritis. [PDF]

open access: yesGenet Res (Camb)
Jiang R   +7 more
europepmc   +1 more source
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Functional Diversity among Notch1, Notch2, and Notch3 Receptors

Biochemical and Biophysical Research Communications, 2002
To clarify functional diversities among the Notch receptors, we generated truncated forms of Notch1, Notch2, and Notch3 comprising the intracellular domain (aN1, aN2, and aN3) and investigated their transcriptional activities for HES1 and HES5 promoters driving the luciferase reporter gene (HES1-Luc and HES5-Luc).
Kiyoshi, Shimizu   +5 more
openaire   +2 more sources

Phage Selection of Bicyclic Peptide Ligands of the Notch1 Receptor

ChemMedChem, 2015
AbstractPrecise regulation of the Notch signaling pathway is crucial, as increases or deficiencies in signaling are associated with diseases, including a wide range of cancers. Recent studies have demonstrated that monoclonal antibodies that bind and stabilize the structure of the negative regulatory region (NRR) in the extracellular domain of the ...
Charlotte, Urech-Varenne   +2 more
openaire   +2 more sources

Physical Interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 Receptors

Biochemical and Biophysical Research Communications, 2000
The Delta/Serrate/LAG-2 (DSL) domain-containing proteins, Delta1, Jagged1, and Jagged2, are considered to be ligands for Notch receptors. However, the physical interaction between the three DSL proteins and respective Notch receptors remained largely unknown.
K, Shimizu   +4 more
openaire   +2 more sources

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