Results 291 to 300 of about 2,402,104 (309)
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Systemic lupus erthematosus (SLE) is a prototype to autoimmune disease characterized by tissue deposition of autoantibody immune complex formation. However, etiology of disease remains unclaified. Defects of T lymphocytes lead to loss of immunological tolerance and support autoantibody production suggested that they may consistently have a central role
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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
Nature Medicine, 2007Teresa Palomero +2 more
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Targeting the NF-κB signaling pathway in Notch1-induced T-cell leukemia
Nature Medicine, 2006Silvia Buonamici +2 more
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Notch1 functions as a tumor suppressor in mouse skin
Nature Genetics, 2003Pleasantine Mill +2 more
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Endothelial Notch1 Activity Facilitates Metastasis
Cancer Cell, 2017Juan Rodriguez-Vita +2 more
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Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia
Nature, 2014Monique Dail, Qing Li, Jon C Aster
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USP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemia
Signal Transduction and Targeted Therapy, 2018Huizhuang Shan, Yu-Ting Dai
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Epidermal Notch1 Loss Promotes Skin Tumorigenesis by Impacting the Stromal Microenvironment
Cancer Cell, 2009Shadmehr Demehri, Raphael Kopan
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