Results 21 to 30 of about 29,683 (216)

Parathyroid Hormone-related Peptide (hPTHrP) and Parathyroid Hormone-related Peptide Receptor Type 1 (PTHR1) Expression in Human Thymus [PDF]

Journal of Histochemistry & Cytochemistry, 2005
Parathyroid hormone-related peptide (hPTHrP) is expressed in human tissues and regulates cellular proliferation, differentiation, and apoptosis by an autocrine/paracrine loop. In rodent thymus, both parathormone and parathyroid hormone-related peptide (PTHrP) are expressed by thymic epithelial cells (TECs).
Marco, Gessi, Giovanni, Monego, Libero, Lauriola, Nicola, Maggiano, Franco O, Ranelletti   +4 more
openaire   +2 more sources

Role of Parathyroid Hormone and Parathyroid Hormone-Related Protein in Protein-Energy Malnutrition

Frontiers in Bioscience-Landmark, 2023
Parathyroid hormone (PTH) is an endocrine peptide found exclusively in the parathyroid glands, whereas parathyroid hormone-related protein (PTHrP) is expressed in a wide range of tissues and organs and exerts endocrine, paracrine, and autocrine actions ...
Praopilad Srisuwarn, Sinee Disthabanchong   +1 more
doaj   +1 more source

Over‐expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma [PDF]

International Journal of Cancer, 2007
AbstractOsteosarcoma is the most common primary bone malignancy in children and is associated with rapid bone growth. Parathyroid hormone‐related peptide (PTHrP) signaling via parathyroid hormone Type 1 receptor (PTHR1) is important for skeletal development and is involved in bone metastases in other tumors. The aim of this study was to investigate the
Rui, Yang, Bang H, Hoang, Tadahiko, Kubo, Hirotaka, Kawano, Alexander, Chou, Rebecca, Sowers, Andrew G, Huvos, Paul A, Meyers, John H, Healey, Richard, Gorlick   +9 more
openaire   +2 more sources

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source

Human Parathyroid Hormone Analog (3–34/29–34) promotes wound re-epithelialization through inducing keratinocyte migration and epithelial–mesenchymal transition via PTHR1-PI3K/AKT activation

Cell Communication and Signaling, 2023
Background Re-epithelialization is important in the process of wound healing. Various methods have been identified to expedite the process, but their clinical application remains limited.
Chunhao Zhou, Donghua Guan, Jialiang Guo, Shangbo Niu, Zhihai Cai, Chengfu Li, Chenghe Qin, Wenjuan Yan, Dehong Yang   +8 more
doaj   +1 more source

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

BJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek, M. Almquist, A. O. Bergenfelz, T. J. Musholt, E. Nordenström, on behalf of the EUROCRINE® Council, M. Almquist, M. Barczynski, L. Brunaud, T. Clerici, M. H. Hansen, M. Iacobone, Ö. Makay, F. F. Palazzo, N. Muñoz‐Pérez, M. Raffaelli, P. Riss, S. van Slycke, M. R. Vriens   +18 more
wiley   +1 more source

Parathyroid hormone attenuates osteoarthritis pain by remodeling subchondral bone in mice

eLife, 2021
Osteoarthritis, a highly prevalent degenerative joint disorder, is characterized by joint pain and disability. Available treatments fail to modify osteoarthritis progression and decrease joint pain effectively. Here, we show that intermittent parathyroid
Qi Sun, Gehua Zhen, Tuo Peter Li, Qiaoyue Guo, Yusheng Li, Weiping Su, Peng Xue, Xiao Wang, Mei Wan, Yun Guan, Xinzhong Dong, Shaohua Li, Ming Cai, Xu Cao   +13 more
doaj   +1 more source

Parathyroid hormone‐like hormone plays a dual role in neuroblastoma depending on PTH1R expression

Molecular Oncology, 2019
We have previously reported the expression of parathyroid hormone‐like hormone (PTHLH) in well‐differentiated, Schwannian stroma‐rich neuroblastic tumors.
Marta García, Carlos Javier Rodríguez‐Hernández, Silvia Mateo‐Lozano, Sara Pérez‐Jaume, Eliana Gonçalves‐Alves, Cinzia Lavarino, Jaume Mora, Carmen deTorres   +7 more
doaj   +1 more source

Markers of Kidney Tubular Function Deteriorate While Those of Kidney Tubule Health Improve in Primary Aldosteronism After Targeted Treatments

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Targeted treatment with mineralocorticoid receptor antagonists (MRAs) or adrenalectomy in patients with primary aldosteronism (PA) causes a decline in estimated glomerular filtration rate; however, the associated simultaneous changes in ...
Vin‐Cent Wu, Chieh‐Kai Chan, Jeff S. Chueh, Yung‐Ming Chen, Yen‐Hung Lin, Chin‐Chen Chang, Po‐Chih Lin, Shiu‐Dong Chung   +7 more
doaj   +1 more source

PTH1 receptor is involved in mediating cellular response to long-chain polyunsaturated fatty acids. [PDF]

PLoS ONE, 2012
The molecular pathways by which long chain polyunsaturated fatty acids (LCPUFA) influence skeletal health remain elusive. Both LCPUFA and parathyroid hormone type 1 receptor (PTH1R) are known to be involved in bone metabolism while any direct link ...
Jose Candelario, Hesam Tavakoli, Mirianas Chachisvilis   +2 more
doaj   +1 more source