Results 201 to 210 of about 1,312,828 (285)

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

A G-type lectin receptor-like kinase TaSRLK confers wheat resistance to stripe rust by regulating the reactive oxygen species signaling pathway. [PDF]

Stress Biol
Niu E, Zhang Y, Xu H, Xu B, Liang Q, Li H, Wang J.   +6 more
europepmc   +1 more source

Evolutionary Dynamics of the Leucine-Rich Repeat Receptor-Like Kinase (LRR-RLK) Subfamily in Angiosperms1[OPEN]

Plant Physiology, 2016
I. Fischer, A. Diévart, G. Droc, Jean-François Dufayard, N. Chantret   +4 more
semanticscholar   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

The maize disease resistance gene Htn1 against northern corn leaf blight encodes a wall-associated receptor-like kinase

Proceedings of the National Academy of Sciences of the United States of America, 2015
S. Hurni, Daniela Scheuermann, S. Krattinger, Bettina Kessel, T. Wicker, Gerhard Herren, Mirjam N Fitze, J. Breen, T. Presterl, M. Ouzunova, B. Keller   +10 more
semanticscholar   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

The receptor-like kinase ARK controls symbiotic balance across land plants. [PDF]

Proc Natl Acad Sci U S A
Sgroi M, Hoey D, Medina Jimenez K, Bowden SL, Hope M, Wallington EJ, Schornack S, Bravo A, Paszkowski U.   +8 more
europepmc   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Comprehensive Genome-Wide Characterization of L-Type Lectin Receptor-like Kinase (L-LecRLK) Genes in Wheat (<i>Triticum aestivum</i> L.) and Their Response to Abiotic Stress. [PDF]

Plants (Basel)
Zhao W, Zhang F, Wang J, Fang S, Cheng Z, Ma X, Fan J, Xu Z, Chen X.   +8 more
europepmc   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source