Results 21 to 30 of about 1,312,828 (285)

Necroptotic kinases are involved in the reduction of depression-induced astrocytes and fluoxetine’s inhibitory effects on necroptotic kinases

Frontiers in Pharmacology, 2023
The role of astrocytes in major depressive disorder has received great attention. Increasing evidence indicates that decreased astrocyte numbers in the hippocampus may be associated with depression, but the role of necroptosis in depression is unknown ...
Salman Zeb, Salman Zeb, Salman Zeb, Huan Ye, Yuan Liu, Hua-Ping Du, Yi Guo, Yi Guo, Yi Guo, Yong-Ming Zhu, Yong-Ming Zhu, Yong-Ming Zhu, Yong Ni, Yong Ni, Yong Ni, Yong Ni, Hui-Ling Zhang, Hui-Ling Zhang, Hui-Ling Zhang, Yuan Xu   +19 more
doaj   +1 more source

The Arabidopsis leucine-rich repeat receptor-like kinase MIK2 is a crucial component of early immune responses to a fungal-derived elicitor.

New Phytologist, 2020
Fusarium spp. cause severe economic damage in many crops, exemplified by Panama Disease of banana or Fusarium head blight of wheat. Plants sense immunogenic patterns (termed elicitors) at the cell surface to initiate pattern-triggered immunity (PTI ...
Alexander D. Coleman, J. Maroschek, L. Raasch, F. Takken, Stefanie Ranf, R. Hückelhoven   +5 more
semanticscholar   +1 more source

Computational identification of receptor-like kinases “RLK” and receptor-like proteins “RLP” in legumes [PDF]

BMC Genomics, 2020
AbstractBackgroundIn plants, the plasma membrane is enclosed by the cell wall and anchors RLK and RLP proteins, which play a fundamental role in perception of developmental and environmental cues and are crucial in plant development and immunity. These plasma membrane receptors belong to large gene/protein families that are not easily classified ...
Daniel Restrepo-Montoya, Robert Brueggeman, Phillip E. McClean, Juan M. Osorno   +3 more
openaire   +3 more sources

The Role of Plasmodesmata-Associated Receptor in Plant Development and Environmental Response

Plants, 2020
Over the last decade, plasmodesmata (PD) symplasmic nano-channels were reported to be involved in various cell biology activities to prop up within plant growth and development as well as environmental stresses. Indeed, this is highly influenced by their
Minh Huy Vu, Arya Bagus Boedi Iswanto, Jinsu Lee, Jae-Yean Kim   +3 more
doaj   +1 more source

EWR1 as a SCOOP peptide activates MIK2-dependent immunity in Arabidopsis

Journal of Plant Interactions, 2022
Phytocytokines are plant peptide signals perceived by plasma membrane-localized receptors in regulating plant immunity. It was recently reported that the phytocytokine SERINE-RICH ENDOGENOUS PEPTIDE12 (SCOOP12) is recognized by the receptor kinase MALE ...
Jie Zhang, Jinxiu Zhao, Yifei Yang, Qixin Bao, Yuxi Li, Hongbo Wang, Shuguo Hou   +6 more
doaj   +1 more source

The promoting effect of modified Dioscorea pills on vascular remodeling in chronic cerebral hypoperfusion via the Ang/Tie signaling pathway

Translational Neuroscience, 2023
The objective of this study was to investigate the effect of modified Dioscorea pills (MDP) on microcirculatory remodeling in the hippocampus of rats with chronic cerebral hypoperfusion (CCH) through the angiopoietin (Ang)/tyrosine kinase receptor ...
Kuang Guiying, Shu Zhigang, Zhu Chunli, Li Hongbing, Zhang Cheng   +4 more
doaj   +1 more source

Cross-kingdom analyses of transmembrane protein kinases show their functional diversity and distinct origins in protists

Computational and Structural Biotechnology Journal, 2023
Transmembrane kinases (TMKs) are important mediators of cellular signaling cascades. The kinase domains of most metazoan and plant TMKs belong to the serine/threonine/tyrosine kinase (S/T/Y-kinase) superfamily. They share a common origin with prokaryotic
Zhiyuan Yin, Danyu Shen, Yaning Zhao, Hao Peng, Jinding Liu, Daolong Dou   +5 more
doaj   +1 more source

Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage

Virulence, 2021
Thousands of human deaths occur annually due to Japanese encephalitis (JE), caused by Japanese encephalitis virus. During the virus infection of the central nervous system, reactive gliosis, uncontrolled inflammatory response, and neuronal cell death are
Usama Ashraf, Zhen Ding, Shunzhou Deng, Jing Ye, Shengbo Cao, Zheng Chen   +5 more
doaj   +1 more source

Aging Regulated Through a Stability Model of Insulin/Insulin Growth Factor Receptor Function

Frontiers in Endocrinology, 2021
Mutations of the insulin-like receptor in Drosophila extend lifespan. New research suggests this receptor operates in two modes. The first extends lifespan while slowing reproduction and reducing growth.
Marc Tatar
doaj   +1 more source

Versatile Roles of the Receptor-Like Kinase Feronia in Plant Growth, Development and Host-Pathogen Interaction

International Journal of Molecular Sciences, 2020
As a member of the Catharanthus roseus receptor-like kinase 1-like (CrRLK1L) protein kinase subfamily, FERONIA (FER) has emerged as a versatile player regulating multifaceted functions in growth and development, as well as responses to environmental ...
Dongchao Ji, Tong Chen, Zhanquan Zhang, Boqiang Li, S. Tian   +4 more
semanticscholar   +1 more source