Results 71 to 80 of about 1,312,828 (285)
Drosophila S6 Kinase like inhibits neuromuscular junction growth by downregulating the BMP receptor thickveins. [PDF]
PLoS Genetics, 2015 Synaptic connections must be precisely controlled to ensure proper neural circuit formation. In Drosophila melanogaster, bone morphogenetic protein (BMP) promotes growth of the neuromuscular junction (NMJ) by binding and activating the BMP ligand ...
Guoli Zhao +7 more
doaj +1 more source
The Receptor-Like Kinase AtVRLK1 Regulates Secondary Cell Wall Thickening1[OPEN]
Plant Physiology, 2018 AtVRLK1 functions as a signaling component in coordinating cell elongation and cell wall thickening during growth and development. During the growth and development of land plants, some specialized cells, such as tracheary elements, undergo secondary ...
Cheng Huang +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Frontiers in Plant Science, 2018 Receptor-like kinases form the largest family of receptors in plants and play an important role in recognizing pathogen-associated molecular patterns and modulating the plant immune responses to invasive fungi, including cereal defenses against fungal ...
Ganesh Thapa +5 more
doaj +1 more source
Receptor‐like kinase activity in membranes of Arabidopsis thaliana [PDF]
FEBS Letters, 1993 A class of protein kinases in the plant Arabidopsis thaliana has been identified which has biochemical characteristics similar to those of the animal receptor protein kinases. These plant protein kinases are membrane‐associated, glycosylated, exhibit a preference for Mn2+ relative to Mg2+, and range from 115 to 135 kDa when identified by renaturation ...
Schaller, G.Eric, Bleecker, Anthony B.
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Lectin receptor kinases in plant innate immunity
Frontiers in Plant Science, 2013 A key feature of innate immunity is the ability to recognize and respond to potential pathogens in a highly sensitive and specific manner. In plants, the first layer of defense is induced after recognition by pattern recognition receptors of microbe ...
Prashant eSingh, Laurent eZimmerli
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Frontiers in Plant Science, 2017 Kinases are primary regulators of plant metabolism and excellent targets for plant breeding. However, most kinases, including the abundant receptor-like kinases (RLK), have no assigned role.
Bruno Aquino +12 more
doaj +1 more source
Ligand-Induced Receptor-like Kinase Complex Regulates Floral Organ Abscission in Arabidopsis.
Cell Reports, 2016 Abscission is a developmental process that enables plants to shed unwanted organs. In Arabidopsis, the floral organ abscission is regulated by a signaling pathway consisting of the peptide ligand IDA, the receptor-like kinases (RLKs) HAE and HSL2, and a ...
Xiangzong Meng +7 more
semanticscholar +1 more source