Results 121 to 130 of about 7,559,498 (434)
Adhesion of membranes via receptor-ligand complexes: Domain formation, binding cooperativity, and active processes [PDF]
, 2009 Cell membranes interact via anchored receptor and ligand molecules. Central questions on cell adhesion concern the binding affinity of these membrane-anchored molecules, the mechanisms leading to the receptor-ligand domains observed during adhesion, and the role of cytoskeletal and other active processes.
arxiv +1 more source
Steroid Hormones and Endocrine Disruptors: Recent Advances in Receptor–Mediated Actions [PDF]
, 2001 It has been accepted that receptor-mediated action of steroid hormones depends on both the receptor and the hormonal level. The mechanism of transcription by steroid receptors is mediated by cofactors, which function as co-activators or co-repressors,
Indarto, Dono, Izawa, Masao
core
Immunoregulatory mechanisms of the arachidonic acid pathway in cancer
FEBS Letters, EarlyView.The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine +3 more
wiley +1 more source
Human interleukin-1 receptor antagonist is expressed in liver [PDF]
, 1992 Using PCR and Northern blot analysis, an IL-1 receptor antagonist specific transcript was amplified from HepG2- and liver mRNA, cDNA clones coding for IL-1 receptor antagonist were isolated from a liver cDNA library and sequence comparison revealed ...
Estaller, C. +3 more
core +1 more source
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia.
New England Journal of Medicine, 2013 Chimeric antigen receptor-modified T cells with specificity for CD19 have shown promise in the treatment of chronic lymphocytic leukemia (CLL). It remains to be established whether chimeric antigen receptor T cells have clinical activity in acute ...
S. Grupp +12 more
semanticscholar +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Plasmodium vivax in vitro continuous culture: the spoke in the wheel
Malaria Journal, 2018 Understanding the life cycle of Plasmodium vivax is fundamental for developing strategies aimed at controlling and eliminating this parasitic species.
Maritza Bermúdez +4 more
doaj +1 more source
Crystal Structure of the β2Adrenergic Receptor-Gs protein complex
Nature, 2011 G protein-coupled receptors (GPCRs) are responsible for the majority of cellular responses to hormones and neurotransmitters as well as the senses of sight, olfaction and taste.
S. Rasmussen +19 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva +1 more
wiley +1 more source
Dynamics of cooperativity in chemical sensing among cell-surface receptors [PDF]
, 2011 Cooperative interactions among sensory receptors provide a general mechanism to increase the sensitivity of signal transduction. In particular, bacterial chemotaxis receptors interact cooperatively to produce an ultrasensitive response to chemoeffector concentrations.
arxiv +1 more source