Results 181 to 190 of about 112,514 (282)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Global knowledge mapping of receptor activator of nuclear factor kappa-B ligand in osteoporotic fractures: a bibliometric analysis (2001-2024). [PDF]

Front Mol Biosci
Lu S, Shen H, Li M, Luo Y, Sun H, Zhao X, Chen J, Bai R, Han P, Zha Y, Jiang X.   +10 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

RNA interference-mediated osteoprotegerin silencing increases the receptor activator of nuclear factor-kappa B ligand/osteoprotegerin ratio and promotes osteoclastogenesis. [PDF]

World J Stem Cells
Wei SG, Chen HH, Xie LR, Qin Y, Mai YY, Huang LH, Liao HB.   +6 more
europepmc   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Combined effect of micro-osteoperforation and vibration on interleukin-1B, receptor activator of nuclear factor kappa-B ligand, C-C motif chemokine ligand 2, and tumor necrosis factor-alpha in orthodontic patients: A parallel-design randomized clinical trial. [PDF]

Dent Res J (Isfahan)
Gholamrezayi E, Sarmadi S, Samimi SM, Ghadirian H.   +3 more
europepmc   +1 more source

Resveratrol Ameliorates Allergic Rhinitis by Activating SIRT1 to Disrupt the Mitochondrial ROS‐Inflammation Vicious Cycle

Flavour and Fragrance Journal, EarlyView.
This study demonstrates that resveratrol alleviates allergic rhinitis by activating SIRT1, thereby disrupting the mitochondrial ROS‐inflammatory cycle, improving mitochondrial function, promoting anti‐inflammatory M2 macrophage polarisation, and reducing epithelial oxidative damage.
Xinyu Zhou, Yi Yue, Wenwen Qi, Wenqing Zhu, Xinran Liu, Rongcui Sui, Xuanchen Zhou   +6 more
wiley   +1 more source

Early and multiple doses of zoledronate mitigates rebound bone loss following withdrawal of receptor activator of nuclear factor kappa-B ligand inhibition. [PDF]

J Bone Miner Res
Kim AS, Taylor VE, Castro-Martinez A, Dhakal S, Zamerli A, Mohanty ST, Xiao Y, Simic MK, Pantalone A, Chu J, Cheng TL, Croucher PI, Center JR, Girgis CM, McDonald MM.   +14 more
europepmc   +1 more source

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

Food Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng, Ning Zhou, Jinqian Yu, Yanling Geng, Xiao Wang, Yannan Chen   +5 more
wiley   +1 more source

Isorhamnetin ameliorates ovariectomy-induced osteoporosis in female rats by regulating the receptor activator of nuclear factor kappa B ligand, osteoprotegerin, bone morphogenetic protein 2 and runt-related transcription factor 2 signaling pathway. [PDF]

J Vet Med Sci
Jiao H, Zheng K.
europepmc   +1 more source