Results 1 to 10 of about 391,709 (316)

Impact of the Central Histaminergic and Melanocortin Systems on Leptin-Induced Hypophagia in Neonatal Layer Chicken [PDF]

open access: yesArchives of Razi Institute, 2021
The present study aimed to assess the probable impact of the central histaminergic and melanocortin systems on leptin-induced hypophagia in neonatal layer chickens.
M Shalikar   +3 more
doaj   +1 more source

Role of Dopaminergic and Cannabinoidergic Receptors on Ghrelin-Induced Hypophagia in 5-Day-Old Broiler Chicken [PDF]

open access: yesArchives of Razi Institute, 2021
The present study aimed to identify the role of dopaminergic and cannabinoidergic systems in the ghrelin-induced hypophagia among meat-type chickens.
R Farrokhi   +4 more
doaj   +1 more source

Interaction of central kisspeptin with melanocortin, GABAergic, corticotrophin, and NPY systems on food intake in chickens [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology, 2022
Kisspeptin is a key component of reproduction that can directly affect food intake in mammals. There is evidence suggesting that melanocortin, GABA, corticotrophin, and neuropeptide Y (NPY), have a mediatory role in reward; however, how these substances ...
Ahmadreza Kord   +4 more
doaj   +1 more source

In vivo Evidence for Brain Region-Specific Molecular Interactions Between Cannabinoid and Orexin Receptors

open access: yesFrontiers in Neuroscience, 2021
The endocannabinoid and orexin neuromodulatory systems serve key roles in many of the same biological functions such as sleep, appetite, pain processing, and emotional behaviors related to reward.
Hye Ji J. Kim   +7 more
doaj   +1 more source

Interaction of Central Glutamatergic and Histaminergic Systems on Food Intake Regulation in Layer Chickens [PDF]

open access: yesArchives of Razi Institute, 2021
This study purposed to discover the connection between the central glutamatergic and histaminergic systems on feeding behavior in layer chickens. In the first experiment, chicks obtained intracerebroventricular (ICV) injections of saline (control ...
M Mobarhan Fard   +3 more
doaj   +1 more source

Peptide Radioligands in Cancer Theranostics: Agonists and Antagonists

open access: yesPharmaceuticals, 2023
The clinical success of radiolabeled somatostatin analogs in the diagnosis and therapy—“theranostics”—of tumors expressing the somatostatin subtype 2 receptor (SST2R) has paved the way for the development of a broader panel of peptide radioligands ...
Berthold A. Nock   +4 more
doaj   +1 more source

Eritoran Attenuates Hepatic Inflammation and Fibrosis in Mice with Chronic Liver Injury

open access: yesCells, 2021
Toll-like receptor 4 (TLR4) signaling plays a key role in liver inflammation and fibrosis. The therapeutic effects of eritoran, a TLR4 antagonist, in mice with chronic liver injury remained unclear. C57BL/6 mice were fed a fast-food diet (FFD) or treated
Yun-Cheng Hsieh   +6 more
doaj   +1 more source

Effects of a novel bradykinin B1 receptor antagonist and angiotensin II receptor blockade on experimental myocardial infarction in rats. [PDF]

open access: yesPLoS ONE, 2012
The aim of the present study was to evaluate the cardiovascular effects of the novel bradykinin B1 receptor antagonist BI-113823 following myocardial infarction (MI) and to determine whether B1 receptor blockade alters the cardiovascular effects of an ...
Dongmei Wu   +4 more
doaj   +1 more source

Lipidated Calcitonin Gene-Related Peptide (CGRP) Peptide Antagonists Retain CGRP Receptor Activity and Attenuate CGRP Action In Vivo

open access: yesFrontiers in Pharmacology, 2022
Signaling through calcitonin gene-related peptide (CGRP) receptors is associated with pain, migraine, and energy expenditure. Small molecule and monoclonal antibody CGRP receptor antagonists that block endogenous CGRP action are in clinical use as anti ...
Aqfan Jamaluddin   +13 more
doaj   +1 more source

Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist

open access: yeseLife, 2019
Immune regulation is a finely balanced process of positive and negative signals. PD-L1 and its receptor PD-1 are critical regulators of autoimmune, antiviral and antitumoural T cell responses.
Kevin W Ng   +6 more
doaj   +1 more source

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