Impact of the Central Histaminergic and Melanocortin Systems on Leptin-Induced Hypophagia in Neonatal Layer Chicken [PDF]
The present study aimed to assess the probable impact of the central histaminergic and melanocortin systems on leptin-induced hypophagia in neonatal layer chickens.
M Shalikar+3 more
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Role of Dopaminergic and Cannabinoidergic Receptors on Ghrelin-Induced Hypophagia in 5-Day-Old Broiler Chicken [PDF]
The present study aimed to identify the role of dopaminergic and cannabinoidergic systems in the ghrelin-induced hypophagia among meat-type chickens.
R Farrokhi+4 more
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Interaction of central kisspeptin with melanocortin, GABAergic, corticotrophin, and NPY systems on food intake in chickens [PDF]
Kisspeptin is a key component of reproduction that can directly affect food intake in mammals. There is evidence suggesting that melanocortin, GABA, corticotrophin, and neuropeptide Y (NPY), have a mediatory role in reward; however, how these substances ...
Ahmadreza Kord+4 more
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The endocannabinoid and orexin neuromodulatory systems serve key roles in many of the same biological functions such as sleep, appetite, pain processing, and emotional behaviors related to reward.
Hye Ji J. Kim+7 more
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Interaction of Central Glutamatergic and Histaminergic Systems on Food Intake Regulation in Layer Chickens [PDF]
This study purposed to discover the connection between the central glutamatergic and histaminergic systems on feeding behavior in layer chickens. In the first experiment, chicks obtained intracerebroventricular (ICV) injections of saline (control ...
M Mobarhan Fard+3 more
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Peptide Radioligands in Cancer Theranostics: Agonists and Antagonists
The clinical success of radiolabeled somatostatin analogs in the diagnosis and therapy—“theranostics”—of tumors expressing the somatostatin subtype 2 receptor (SST2R) has paved the way for the development of a broader panel of peptide radioligands ...
Berthold A. Nock+4 more
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Eritoran Attenuates Hepatic Inflammation and Fibrosis in Mice with Chronic Liver Injury
Toll-like receptor 4 (TLR4) signaling plays a key role in liver inflammation and fibrosis. The therapeutic effects of eritoran, a TLR4 antagonist, in mice with chronic liver injury remained unclear. C57BL/6 mice were fed a fast-food diet (FFD) or treated
Yun-Cheng Hsieh+6 more
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Effects of a novel bradykinin B1 receptor antagonist and angiotensin II receptor blockade on experimental myocardial infarction in rats. [PDF]
The aim of the present study was to evaluate the cardiovascular effects of the novel bradykinin B1 receptor antagonist BI-113823 following myocardial infarction (MI) and to determine whether B1 receptor blockade alters the cardiovascular effects of an ...
Dongmei Wu+4 more
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Signaling through calcitonin gene-related peptide (CGRP) receptors is associated with pain, migraine, and energy expenditure. Small molecule and monoclonal antibody CGRP receptor antagonists that block endogenous CGRP action are in clinical use as anti ...
Aqfan Jamaluddin+13 more
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Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist
Immune regulation is a finely balanced process of positive and negative signals. PD-L1 and its receptor PD-1 are critical regulators of autoimmune, antiviral and antitumoural T cell responses.
Kevin W Ng+6 more
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