Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
NEUROPHARMACOLOGICAL ACTIONS OF TWO NEW ADRENERGIC BETA-RECEPTOR ANTAGONISTS, BUNOLOL AND H 64/52
, 1972 N K Khanna +3 more
openalex +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Adrenergic pathways in glycine-mediated feeding behavior: Evidence from layer chickens
Poultry ScienceGlycinergic and adrenergic systems are integral to the regulation of meal consumption in avian species; however, the interactions between these systems have not been previously documented. This investigation was conducted to explore the interplay between
Hamed Zarei +2 more
doaj
EFFECTS OF H2‐RECEPTOR ANTAGONISTS AND ANTICHOLINOCEPTOR DRUGS ON GASTRIC AND SALIVARY SECRETION INDUCED BY BETHANECHOL IN THE ANAESTHETIZED DOG [PDF]
, 1982 M J Daly, J. M. Humphray, R. Stables
openalex +1 more source
LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor.
Cell Metabolism, 2017 Xuecai Ge +15 more
semanticscholar +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Effects of temperature and ethanol on agonist and antagonist binding to rat heart muscarinic receptors in the absence and presence of GTP [PDF]
, 1985 Magalì Waelbroeck +4 more
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
The Effect of Metiamide, An H2-Receptor Antagonist, in the Prevention of Experimental Stress Ulcers
, 1976 S Safaie-Shirazi +2 more
openalex +1 more source