Results 11 to 20 of about 713,346 (360)
Leukotriene Receptor Antagonists [PDF]
Seminars in Respiratory and Critical Care Medicine, 2002 In the past decade, heightened emphasis has been placed on the importance of inflammation in the pathogenesis of asthma. Although corticosteroids have remained the primary anti-inflammatory agents in the management of the persistent asthmatic, new classes of drugs have recently been added.
Marzena E, Krawiec, Nizar J, Jarjour
openaire +2 more sources
Olfaction: Receptor Antagonistes [PDF]
Current Biology, 2020 Odor receptors of the mammalian olfactory system have long been known to be activated in combinatorial fashion by odorants. A large-scale study now reveals that inhibition of receptors by odorants is comparably prevalent and combinatorial.
Douglas, Rioux, John R, Carlson
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Journal of Pharmacological Sciences, 2010 We investigated pharmacological characteristics of the itch-associated response to chronic dermatitis induced by 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one (oxazolone) repeated application in mice.
Yukihito Tsukumo +2 more
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Interaction of hypothalamic GABA\u3csub\u3eA\u3c/sub\u3e and excitatory amino acid receptors controlling heart rate in rats [PDF]
, 1991 We have previously shown that microinjection of drugs that impair gamma-aminobutyric acid (GABA)-mediated synaptic inhibition into the dorsomedial hypothalamus (DMH) of rats generates cardiovascular and behavioral changes that mimic the response to ...
DiMicco, Joseph A., Soltis, Robert P.
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Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist
eLife, 2019 Immune regulation is a finely balanced process of positive and negative signals. PD-L1 and its receptor PD-1 are critical regulators of autoimmune, antiviral and antitumoural T cell responses.
Kevin W Ng +6 more
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A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias [PDF]
, 2017 Free Fatty Acid Receptor 2 is a GPCR activated by short chain fatty acids produced in high levels in the lower gut by microbial fermentation of non-digestible carbohydrates.
Aoki, Junken +9 more
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Frontiers in Pharmacology, 2017 Several evidences indicate that the ubiquitous nucleoside adenosine, acting through A1, A2A, A2B, and A3 receptor (AR) subtypes, plays crucial roles in tumor development. Adenosine has contrasting effects on cell proliferation depending on the engagement
Stefania Gessi +9 more
doaj +1 more source
Correlation of Histamine Receptors and Adrenergic Receptor in Broilers Appetite [PDF]
Archives of Razi Institute, 2022 The current study was conducted to investigate the interaction between the central adrenergic and histaminergic systems and the broiler chick’s feed intake.
M Daneshvar +3 more
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Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. [PDF]
, 2014 Perampanel is an aryl substituted 2-pyridone AMPA receptor antagonist that was recently approved as a treatment for epilepsy. The drug potently inhibits AMPA receptor responses but the mode of block has not been characterized.
Chen, Chao-Yin +3 more
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Involvement of central opiate receptors in modulation of centrally administered oxytocin-induced antinociception [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): Oxytocin is involved in modulation of many brain-mediated functions. In the present study, we investigated the central effects of oxytocin and its receptor antagonist, atosiban on inflammatory pain.
Amir Erfanparast +2 more
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