Results 211 to 220 of about 391,709 (316)

Transfer of the Oral Gonadotropin-Releasing Hormone Receptor Antagonist Relugolix Into Breast Milk of Healthy Lactating Women. [PDF]

Pharmacol Res Perspect
Brimhall DB, Chen YL, Lee S, Yoshida K, Ufer M.   +4 more
europepmc   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Interleukin-1 receptor antagonist overexpression in mesenchymal stem cells improves hemorrhagic cystitis outcomes via HtrA serine peptidase 3. [PDF]

Stem Cell Res Ther
Song J, Han Y, Chen Y, Cheng L, Xiao J, Li A, Kong D, Jiang Y, Zheng C.   +8 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Mineralocorticoid Receptor Antagonist Use Among Patients With Chronic Kidney Disease Who Transitioned to Dialysis. [PDF]

Kidney Med
Tong EM, Zhou H, Pak K, Huang CW, Broder BI, Sim JJ.   +5 more
europepmc   +1 more source

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

The efficacy and safety of mirabegron and α-adrenergic receptor antagonist in the treatment of distal ureteral stones: a systematic review and meta-analysis. [PDF]

Front Pharmacol
Guo Y, Sun F, Wang Y, Li Y, Wang T, Ma X, Wu J.   +6 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Correction to: Preparation and preliminary evaluation of a tritium-labeled allosteric P2X4 receptor antagonist. [PDF]

Purinergic Signal
Nagel J, Törmäkangas O, Kuokkanen K, El-Tayeb A, Messinger J, Abdelrahman A, Bous C, Schiedel AC, Müller CE.   +8 more
europepmc   +1 more source

A synthetic peptide derivative that is a cholecystokinin receptor antagonist.

, 1987
M. F. Lignon, Marie‐Christine Galas, Mariano Rodríguez, Jeanine Laur, André Aumelas, Jean Martínez   +5 more
openalex   +1 more source