Results 241 to 250 of about 3,169,653 (411)

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Steroidal Mineralocorticoid Receptor Antagonist Side Effects and Reasons for Discontinuation: A Patient Survey (RELICS-PS). [PDF]

Pragmat Obs Res
Richard EL, Stephenson JJ, Desai NR, Willey VJ, Gay A, Scott C, Folkerts K, Pessina E, Singh R, Teng CC, Oberprieler NG.   +10 more
europepmc   +1 more source

Preclinical pharmacology of perampanel, a selective non‐competitive AMPA receptor antagonist

Acta Neurologica Scandinavica, Supplementum, 2013
Michael A. Rogawski, Takahisa Hanada
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Agonist versus antagonist binding to alpha-adrenergic receptors.

, 1980
Brian B. Hoffman, Thomas Michel, D. M. Kilpatrick, Robert J. Lefkowitz, Margaret E. M. Tolbert, H R Gilman, John N. Fain   +6 more
openalex   +1 more source

In vivo and in vitro activity of selective 5‐hydroxytryptamine₂ receptor antagonists [PDF]

, 1986
Sean Conolan, Michael J. Quinn, David A. Taylor   +2 more
openalex   +1 more source

Comparison of Somatostatin Receptor Agonist and Antagonist for Peptide Receptor Radionuclide Therapy: A Pilot Study

Journal of Nuclear Medicine, 2014
D. Wild, M. Fani, Richard Fischer, L. Del Pozzo, F. Kaul, S. Krebs, Richard Fischer, J. Rivier, J. Reubi, H. Maecke, W. Weber   +10 more
semanticscholar   +1 more source

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

Molecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

Discovery of Palazestrant (OP-1250), a Potent and Orally Bioavailable Complete Estrogen Receptor Antagonist (CERAN) and Selective Estrogen Receptor Degrader (SERD). [PDF]

ACS Omega
Ng RA, Barratt S, Parisian A, Palanisamy GS, Phukan S, Sun R, Robello B, Peña G, Sapugay J, Yeghikyan D, Wang C, Satish Kher S, Thangathirupathy S, Millikin R, Yu G, Watanabe T, Zhou F, Rich B, Duncan A, Andersen SE, Chawla R, Zak DR, Heerding DA, Hearn BR, Greene G, Harmon CL, Hodges-Gallagher L, Kushner PJ, Fanning SW, Myles DC.   +29 more
europepmc   +1 more source

The antisecretory effects of zaltidine, a novel long‐acting H2‐receptor antagonist, in healthy volunteers and in subjects with a past history of duodenal ulcer. [PDF]

, 1986
Godfrey LaFerla, N. Buchanan, J Hearns, GP Crean, K E McColl, AT Clucas   +5 more
openalex   +1 more source